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General Information
ZIRC
ZFIN ID: ZDB-FIG-160927-63
Díaz-Casado et al., 2016 - Melatonin rescues zebrafish embryos from the parkinsonian phenotype restoring the Parkin/PINK1/DJ-1/MUL1 network. Journal of pineal research   61(1):96-107 Full text @ J. Pineal Res.
ADDITIONAL FIGURES
EXPRESSION / LABELING:
Genes:
Fish:
Conditions:
Anatomical Term:
Stage: Day 5
PHENOTYPE:
Fish:
Conditions:
Observed In:
Stage Range: Protruding-mouth to Day 5

Fig. 5 ZFIN is incorporating published figure images and captions as part of an ongoing project. Figures from some publications have not yet been curated, or are not available for display because of copyright restrictions.

Gene Expression Details
Gene Antibody Fish Conditions Stage Anatomy Assay
mul1a AB control Day 5 whole organism RTPCR
AB chemical treatment by environment: 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine Day 5 whole organism RTPCR
AB chemical treatment by environment: melatonin, chemical treatment by environment: 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine Day 5 whole organism RTPCR
nos2a AB control Day 5 whole organism RTPCR
AB chemical treatment by environment: 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine Day 5 whole organism RTPCR
AB chemical treatment by environment: melatonin, chemical treatment by environment: 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine Day 5 whole organism RTPCR
park7 AB control Day 5 whole organism RTPCR
AB chemical treatment by environment: 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine Day 5 whole organism RTPCR
AB chemical treatment by environment: melatonin, chemical treatment by environment: 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine Day 5 whole organism RTPCR
pink1 AB control Day 5 whole organism RTPCR
AB chemical treatment by environment: 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine Day 5 whole organism RTPCR
AB chemical treatment by environment: melatonin, chemical treatment by environment: 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine Day 5 whole organism RTPCR
prkn AB control Day 5 whole organism RTPCR
AB chemical treatment by environment: 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine Day 5 whole organism RTPCR
AB chemical treatment by environment: melatonin, chemical treatment by environment: 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine Day 5 whole organism RTPCR
sncga AB control Day 5 whole organism RTPCR
AB chemical treatment by environment: 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine Day 5 whole organism RTPCR
AB chemical treatment by environment: melatonin, chemical treatment by environment: 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine Day 5 whole organism RTPCR
th AB control Day 5 whole organism RTPCR
AB chemical treatment by environment: 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine Day 5 whole organism RTPCR
AB chemical treatment by environment: melatonin, chemical treatment by environment: 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine Day 5 whole organism RTPCR
Antibody Labeling Details No data available
Phenotype Details
Fish Conditions Stage Phenotype
AB chemical treatment by environment: 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine Protruding-mouth NADH dehydrogenase (ubiquinone) activity decreased occurrence, abnormal
Day 5 NADH dehydrogenase (ubiquinone) activity decreased occurrence, abnormal
Day 5 nervous system inflammatory response increased occurrence, abnormal
Day 5 whole organism prkn expression decreased amount, abnormal
Day 5 whole organism pink1 expression decreased amount, abnormal
Day 5 whole organism mul1a expression decreased amount, abnormal
Day 5 whole organism th expression decreased amount, abnormal
Day 5 whole organism park7 expression decreased amount, abnormal
Day 5 whole organism sncga expression increased amount, abnormal
Day 5 whole organism nos2a expression increased amount, abnormal
AB chemical treatment by environment: melatonin, chemical treatment by environment: 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine Protruding-mouth NADH dehydrogenase (ubiquinone) activity occurrence, ameliorated
Day 5 NADH dehydrogenase (ubiquinone) activity occurrence, ameliorated
Day 5 nervous system inflammatory response occurrence, ameliorated
Day 5 whole organism nos2a expression amount, ameliorated
Day 5 whole organism park7 expression amount, ameliorated
Day 5 whole organism pink1 expression amount, ameliorated
Day 5 whole organism th expression amount, ameliorated
Day 5 whole organism prkn expression amount, ameliorated
Day 5 whole organism sncga expression amount, ameliorated
Day 5 whole organism mul1a expression amount, ameliorated
Full text @ J. Pineal Res.