ZFIN ID: ZDB-FIG-160927-62
Díaz-Casado et al., 2016 - Melatonin rescues zebrafish embryos from the parkinsonian phenotype restoring the Parkin/PINK1/DJ-1/MUL1 network. Journal of pineal research   61(1):96-107 Full text @ J. Pineal Res.
ADDITIONAL FIGURES
EXPRESSION / LABELING:
Genes:
Antibodies:
Fish:
Conditions:
Anatomical Term:
Stage: Protruding-mouth
PHENOTYPE:
Fish:
Conditions:
Observed In:
Stage: Protruding-mouth

Fig. 4 ZFIN is incorporating published figure images and captions as part of an ongoing project. Figures from some publications have not yet been curated, or are not available for display because of copyright restrictions.

Gene Expression Details
Gene Antibody Fish Conditions Stage Qualifier Anatomy Assay
mul1a AB control Protruding-mouth whole organism RTPCR
AB chemical treatment by environment: 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine Protruding-mouth whole organism RTPCR
AB chemical treatment by environment: melatonin, chemical treatment by environment: 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine Protruding-mouth whole organism RTPCR
park7 Ab1-park7 AB control Protruding-mouth whole organism WB
Protruding-mouth whole organism RTPCR
AB chemical treatment by environment: 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine Protruding-mouth whole organism RTPCR
Ab1-park7 Protruding-mouth Not Detected whole organism WB
AB chemical treatment by environment: melatonin, chemical treatment by environment: 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine Protruding-mouth whole organism RTPCR
Ab1-park7 Protruding-mouth whole organism WB
pink1 Ab1-pink1 AB control Protruding-mouth whole organism WB
Protruding-mouth whole organism RTPCR
Ab1-pink1 AB chemical treatment by environment: 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine Protruding-mouth whole organism WB
Protruding-mouth whole organism RTPCR
AB chemical treatment by environment: melatonin, chemical treatment by environment: 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine Protruding-mouth whole organism RTPCR
Ab1-pink1 Protruding-mouth whole organism WB
prkn AB control Protruding-mouth whole organism RTPCR
AB chemical treatment by environment: 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine Protruding-mouth whole organism RTPCR
AB chemical treatment by environment: melatonin, chemical treatment by environment: 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine Protruding-mouth whole organism RTPCR
sncga AB control Protruding-mouth whole organism RTPCR
AB chemical treatment by environment: 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine Protruding-mouth whole organism RTPCR
AB chemical treatment by environment: melatonin, chemical treatment by environment: 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine Protruding-mouth whole organism RTPCR
Antibody Labeling Details
Antibody Assay Fish Conditions Stage Qualifier Anatomy
Ab1-mul1 WB AB control Protruding-mouth whole organism
WB AB chemical treatment by environment: 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine Protruding-mouth whole organism
WB AB chemical treatment by environment: melatonin, chemical treatment by environment: 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine Protruding-mouth whole organism
Ab1-park2 WB AB control Protruding-mouth whole organism
WB AB chemical treatment by environment: 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine Protruding-mouth Not Detected whole organism
WB AB chemical treatment by environment: melatonin, chemical treatment by environment: 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine Protruding-mouth whole organism
Ab2-sncg WB AB control Protruding-mouth Not Detected whole organism
WB AB chemical treatment by environment: 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine Protruding-mouth whole organism
WB AB chemical treatment by environment: melatonin, chemical treatment by environment: 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine Protruding-mouth whole organism
Phenotype Details
Fish Conditions Stage Phenotype
AB chemical treatment by environment: 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine Protruding-mouth whole organism park7 expression absent, abnormal
Protruding-mouth whole organism Ab1-park2 labeling absent, abnormal
Protruding-mouth whole organism prkn expression decreased amount, abnormal
Protruding-mouth whole organism park7 expression decreased amount, abnormal
Protruding-mouth whole organism pink1 expression decreased amount, abnormal
Protruding-mouth whole organism Ab2-sncg labeling increased amount, abnormal
Protruding-mouth whole organism sncga expression increased amount, abnormal
AB chemical treatment by environment: melatonin, chemical treatment by environment: 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine Protruding-mouth whole organism pink1 expression amount, ameliorated
Protruding-mouth whole organism prkn expression amount, ameliorated
Protruding-mouth whole organism Ab1-park2 labeling amount, ameliorated
Protruding-mouth whole organism park7 expression amount, ameliorated
Protruding-mouth whole organism park7 expression amount, ameliorated
Protruding-mouth whole organism Ab2-sncg labeling amount, ameliorated
Protruding-mouth whole organism sncga expression decreased amount, abnormal
Protruding-mouth whole organism Ab1-mul1 labeling increased amount, abnormal
Protruding-mouth whole organism prkn expression increased amount, abnormal
Full text @ J. Pineal Res.