Gene

mul2

ID
ZDB-GENE-050102-5
Name
mitochondrial E3 ubiquitin protein ligase 2
Symbol
mul2 Nomenclature History
Previous Names
  • mul1
  • mul1a (1)
  • zgc:92166 (1)
Type
protein_coding_gene
Location
Chr: 2 Mapping Details/Browsers
Description
Predicted to have identical protein binding activity and ubiquitin-protein transferase activity. Predicted to be involved in several processes, including activation of cysteine-type endopeptidase activity involved in apoptotic process; mitochondrial fission; and positive regulation of I-kappaB kinase/NF-kappaB signaling. Predicted to localize to integral component of mitochondrial outer membrane and peroxisome. Orthologous to human MUL1 (mitochondrial E3 ubiquitin protein ligase 1).
Genome Resources
Note
None
Comparative Information
Expression
All Expression Data
3 figures from 2 publications
Cross-Species Comparison
High Throughput Data
Thisse Expression Data
Wild Type Expression Summary
Phenotype
All Phenotype Data
No data available
Cross-Species Comparison
Alliance
Phenotype Summary
Mutations
Mutants
Sequence Targeting Reagents
Human Disease
Associated With mul2 Human Ortholog
No data available
Associated With mul2 Via Experimental Models
No data available
Gene Ontology
Protein Domains
Domain, Family, and Site Summary
Type InterPro ID Name
Domain IPR001841 Zinc finger, RING-type
Domain IPR022170 E3 Ubiquitin ligase MUL1-like
Family IPR051652 MDM2/MDM4 and MUL1
Homologous_superfamily IPR013083 Zinc finger, RING/FYVE/PHD-type
Domain Details Per Protein
Protein Length E3 Ubiquitin ligase MUL1-like MDM2/MDM4 and MUL1 Zinc finger, RING/FYVE/PHD-type Zinc finger, RING-type
UniProtKB:Q5M7X9 341
Transcripts
Genome Browsers
Type Name Annotation Method Has Havana Data Length (nt) Analysis
mRNA mul1a-201 (1) Ensembl 5,818 nt
Interactions and Pathways
No data available
Antibodies
No data available
Plasmids
No data available
Constructs
Marker Relationships
Sequences
Orthology
Comparative Orthology
Alliance
Gene Tree
Ensembl
Citations