ZFIN ID: ZDB-FIG-160519-1
Dai et al., 2015 - Depletion of suppressor of cytokine signaling-1a causes hepatic steatosis and insulin resistance in zebrafish. American journal of physiology. Endocrinology and metabolism   308(10):E849-59 Full text @ Am. J. Physiol. Endocrinol. Metab.
ADDITIONAL FIGURES
EXPRESSION / LABELING:
Genes:
Antibodies:
Fish:
Condition:
Anatomical Terms:
Stage Range: Prim-5 to Day 5
PHENOTYPE:
Fish:
Condition:
Observed In:
Stage Range: Prim-5 to Adult

Fig. 2 ZFIN is incorporating published figure images and captions as part of an ongoing project. Figures from some publications have not yet been curated, or are not available for display because of copyright restrictions.

Gene Expression Details
Gene Antibody Fish Conditions Stage Anatomy Assay
gata1a AB standard conditions Prim-5 lateral plate mesoderm ISH
socs1aihb33/ihb33(AB) standard conditions Prim-5 lateral plate mesoderm ISH
ifng1 AB standard conditions Day 5 whole organism RTPCR
socs1aihb33/ihb33(AB) standard conditions Day 5 whole organism RTPCR
il1b AB standard conditions Day 5 whole organism RTPCR
socs1aihb33/ihb33(AB) standard conditions Day 5 whole organism RTPCR
il6 AB standard conditions Day 5 whole organism RTPCR
socs1aihb33/ihb33(AB) standard conditions Day 5 whole organism RTPCR
nfkb2 AB standard conditions Day 5 whole organism RTPCR
socs1aihb33/ihb33(AB) standard conditions Day 5 whole organism RTPCR
nfkbiab AB standard conditions Day 5 whole organism RTPCR
socs1aihb33/ihb33(AB) standard conditions Day 5 whole organism RTPCR
tnfa AB standard conditions Day 5 whole organism RTPCR
socs1aihb33/ihb33(AB) standard conditions Day 5 whole organism RTPCR
Antibody Labeling Details
Antibody Assay Fish Conditions Stage Anatomy
Ab1-hbbe1 WB AB standard conditions Day 5 whole organism
WB socs1aihb33/ihb33(AB) standard conditions Day 5 whole organism
WB socs1aihb33/ihb33(AB) chemical treatment: tyrphostin B42 Day 5 whole organism
Ab3-stat5 WB AB control Day 5 whole organism
WB AB standard conditions Day 5 whole organism
WB socs1aihb33/ihb33(AB) control Day 5 whole organism
WB socs1aihb33/ihb33(AB) standard conditions Day 5 whole organism
WB socs1aihb33/ihb33(AB) chemical treatment: tyrphostin B42 Day 5 whole organism
Ab4-stat5 WB AB control Day 5 whole organism
WB AB standard conditions Day 5 whole organism
WB socs1aihb33/ihb33(AB) control Day 5 whole organism
WB socs1aihb33/ihb33(AB) standard conditions Day 5 whole organism
WB socs1aihb33/ihb33(AB) chemical treatment: tyrphostin B42 Day 5 whole organism
Phenotype Details
Fish Conditions Stage Phenotype
socs1aihb33/ihb33(AB) control Day 5 whole organism ab3-stat5 labeling increased amount, abnormal
socs1aihb33/ihb33(AB) standard conditions Prim-5 lateral plate mesoderm gata1a expression increased amount, abnormal
Day 5 whole organism ifng1 expression increased amount, abnormal
Day 5 whole organism il1b expression decreased amount, abnormal
Day 5 whole organism il6 expression decreased amount, abnormal
Day 5 whole organism tnfa expression decreased amount, abnormal
Day 5 whole organism ab1-hbbe1 labeling increased amount, abnormal
Day 5 whole organism ab3-stat5 labeling increased amount, abnormal
Adult nucleate erythrocyte increased amount, abnormal
socs1aihb33/ihb33(AB) chemical treatment: tyrphostin B42 Day 5 whole organism ab1-hbbe1 labeling amount, ameliorated
Day 5 whole organism ab3-stat5 labeling amount, ameliorated
Full text @ Am. J. Physiol. Endocrinol. Metab.