FIGURE

Fig. 10

ID
ZDB-FIG-150615-10
Publication
Krock et al., 2014 - The Par-PrkC Polarity Complex Is Required for Cilia Growth in Zebrafish Photoreceptors
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Fig. 10

Pharmacological inhibition of PrkC activity reduces apical domain size. (A?C) Transverse cryosections of 4 dpf retinas were stained with phalloidin to label actin (red) and zpr-1 to label double cones (green). (A) DMSO-control treated larvae; (B) Larvae treated with 3 μM PrkC inhibitor; (C) Larvae treated with 3 μM control inhibitor. Sections were also counterstained with DAPI (blue). (D) Quantification of apical domain as a percentage of total photoreceptor inner segment length. All values are plotted as a percentage of n/m, as defined in the text. Control = 45%; PrkC inhibitor = 28%; non-myristoylated control inhibitor = 44%. Blue error bars indicate the mean ± standard deviation. Scale bar = 10 μm.

Expression Data
Antibody:
Fish:
Condition:
Anatomical Term:
Stage: Day 4

Expression Detail
Antibody Labeling
Phenotype Data
Fish:
Condition:
Observed In:
Stage: Day 4

Phenotype Detail
Acknowledgments
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