FIGURE

Fig. 2

ID

ZDB-FIG-150511-9

Publication

Otis et al., 2015 - Zebrafish as a model for apolipoprotein biology: Comprehensive expression analysis and a role for ApoA-IV in regulating food intake

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Fig. 2

Developmental mRNA expression patterns of apoA-Ia and apoA-Ib. In situ hybridization of apoA-Ia and apoA-Ib during gastrulation [80-100% epiboly (E)], somitogenesis [15-20 somite (S)], and daily until 6 dpf. Both genes localize to the YSL from somitogenesis through 5 dpf, apoA-Ia localizes to the intestine (I) at 6 dpf, and apoA-Ib localizes strongly to the liver (L) and weakly to the intestine at 6 dpf. All zebrafish are wild type except 6-dpf larvae, which are nacre^-/-. Larvae studied at 2-5 dpf were treated with PTU to prevent pigment formation. No signal was observed for either gene at the eight-cell stage or blastulation (supplementary material Fig. S1). Experiments were performed three times for each gene at each stage with ne5 embryos or larvae per probe per experiment.

Expression Data

Genes:	apoa1a apoa1b
Fish:	AB mitfa^w2/w2
Anatomical Terms:	intestine liver yolk syncytial layer
Stage Range:	75%-epiboly to Day 6

Expression Detail

Antibody Labeling

Phenotype Data

Phenotype Detail

Acknowledgments

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