FIGURE

Fig. 5

ID

ZDB-FIG-150511-12

Publication

Otis et al., 2015 - Zebrafish as a model for apolipoprotein biology: Comprehensive expression analysis and a role for ApoA-IV in regulating food intake

Other Figures

All Figure Page

Back to All Figure Page

Fig. 5

The zebrafish apoA-IV genes have unique expression patterns in the YSL, intestine and liver. Developmental mRNA expression dynamics of the zebrafish apoA-IV genes, as measured by ISH, during somitogenesis [15-20 somite (S)] and at 1-6 dpf. All four apoA-IV genes showed earliest mRNA expression at 15-20 S in the YSL; the mRNAs localize to distinct subregions of the YSL until 5 dpf. All four genes are expressed in the intestine (I) at 4-6 dpf, with weak intestinal expression observed for apoA-IVa, and apoA-IVb.3 is expressed in the liver (L) at 4-6 dpf. No expression was observed for the apoA-IV genes at the eight-cell stage, 30% epiboly or 80-100% epiboly (supplementary material Fig. S4). Larvae from 15-20 S to 5 dpf are wild type (2-5 dpf treated with PTU; 6-dpf larvae are nacre^-/-. Experiments were performed in triplicate with ne5 embryos or larvae per probe in every experiment.

Expression Data

Genes:	apoa4a apoa4b.1 apoa4b.2 apoa4b.3
Fish:	AB mitfa^w2/w2
Anatomical Terms:	intestine liver yolk syncytial layer
Stage Range:	14-19 somites to Day 6

Expression Detail

Antibody Labeling

Phenotype Data

Phenotype Detail

Acknowledgments

This image is the copyrighted work of the attributed author or publisher, and ZFIN has permission only to display this image to its users. Additional permissions should be obtained from the applicable author or publisher of the image. Full text @ Dis. Model. Mech.