FIGURE

Fig. 3

ID

ZDB-FIG-140211-8

Publication

Breau et al., 2013 - A Hox gene controls lateral line cell migration by regulating chemokine receptor expression downstream of Wnt signaling

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Fig. 3

Dominant repressor Hoxb8a down-regulates the expression of cxcr4b and cxcr7b. (A) Fluorescent images of cldnb:lyngfp in cldnb4.2:gal4 x UAS:Hoxb8aEnRHA embryos and control siblings at 45 hpf. Red arrowheads indicate the position of the primordium. (B) Quantification of the migration at 45 hpf (control, n = 56; cldnb4.2:gal4 x UAS:Hoxb8aEnRHA, n = 62). Expression of (C) cxcr4b, (D) cxcr7b, and (E) lef1 in cldnb4.2:gal4 x UAS:Hoxb8aEnRHA and control siblings at 30 hpf. ISH was followed by HA immunostaining (brown). (Scale bar: 25 µm.)

Expression Data

Genes:	ackr3b cxcr4b EGFP lef1
Fish:	zf106Tg nim11Tg; nim13Tg; zf106Tg
Anatomical Terms:	posterior lateral line primordium posterior lateral line primordium posterior-most region
Stage Range:	Prim-15 to High-pec

Expression Detail

Antibody Labeling

Phenotype Data

Fish:	nim11Tg; nim13Tg; zf106Tg
Observed In:	posterior lateral line neuromast primordium migration
Stage:	High-pec

Phenotype Detail

Acknowledgments

This image is the copyrighted work of the attributed author or publisher, and ZFIN has permission only to display this image to its users. Additional permissions should be obtained from the applicable author or publisher of the image. Full text @ Proc. Natl. Acad. Sci. USA