FIGURE

Fig. S4

ID

ZDB-FIG-140211-17

Publication

Breau et al., 2013 - A Hox gene controls lateral line cell migration by regulating chemokine receptor expression downstream of Wnt signaling

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Fig. S4

Hoxb8a knockdown leads to reduced proliferation in the primordium. BrdU incorporation (red) in cldnb:lyngfp (green) embryos in (A) control and (B) Hoxb8a morphants at 24 hfp. The leading zone is defined as the region containing primordium cells caudal to the first forming proneuromast L1. Histograms of the total cell number in (C) L1 and (D) the leading zone of control (n = 11) and Hoxb8a (n = 10) morphant primordia at 24 hpf. Histograms showing the proportion of BrdU postitive cells in (E) L1 and (F) the leading zone of control (n = 11) and Hoxb8a (n = 10) morphant primordia at 24 hpf. **P < 0.005; ***P < 0.001.

Expression Data

Gene:	EGFP
Fish:	zf106Tg zf106Tg + MO2-hoxb8a
Knockdown Reagent:	MO2-hoxb8a
Anatomical Term:	posterior lateral line primordium
Stage:	Prim-5

Expression Detail

Antibody Labeling

Phenotype Data

Fish:	zf106Tg + MO2-hoxb8a
Knockdown Reagent:	MO2-hoxb8a
Observed In:	cell posterior lateral line primordium cell population proliferation posterior lateral line primordium posterior-most region
Stage:	Prim-5

Phenotype Detail

Acknowledgments

This image is the copyrighted work of the attributed author or publisher, and ZFIN has permission only to display this image to its users. Additional permissions should be obtained from the applicable author or publisher of the image. Full text @ Proc. Natl. Acad. Sci. USA