FIGURE

Fig. 5

ID

ZDB-FIG-131029-35

Publication

Novikov et al., 2013 - Tmem88a mediates GATA-dependent specification of cardiomyocyte progenitors by restricting WNT signaling

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Fig. 5

Tmem88a-deficient hearts are small and hypocellular. (A,B) Representative confocal images of control and tmem88a morphant hearts dissected from 51 hpf zebrafish embryos. Morphants were generated in the tg(myl7:DsRed2-nuc) background. Left panels show immunohistochemistry for DsRed2 labeling of cardiomyocyte nuclei (CMs). Middle panels show S46 antibody labeling of atrial cells. Right panels show merge. Atrium (a) and ventricle (v) are indicated. (C) Atrial (a), ventricular (v) and total (T) cardiomyocyte numbers. (D) Atrial, ventricular and total cardiac chamber length. n=6 hearts quantified per condition. ^*P<0.05, ^**P<0.01; error bars indicate s.d.

Expression Data

Gene:	DsRed2
Antibody:	Ab-S46
Fish:	f2Tg f2Tg + MO3-tmem88a + MO4-tmem88a
Knockdown Reagents:	MO3-tmem88a MO4-tmem88a
Anatomical Terms:	atrium cardiac muscle cell nucleus
Stage:	Long-pec

Expression Detail

Antibody Labeling

Phenotype Data

Fish:	f2Tg + MO3-tmem88a + MO4-tmem88a
Knockdown Reagents:	MO3-tmem88a MO4-tmem88a
Observed In:	atrium cardiac muscle cell cardiac ventricle
Stage:	Long-pec

Phenotype Detail

Acknowledgments

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