FIGURE

Fig. S3

ID

ZDB-FIG-111018-26

Publication

Mouillesseaux et al., 2011 - Mutation in utp15 Disrupts Vascular Patterning in a p53-Dependent Manner in Zebrafish Embryos

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Fig. S3

Expression of growth factors is unchanged in LA1908 mutant embryos. Expression of bmp2b (A–D), bmp4 (E–H), and vegfaa (I–L) is indistinguishable between stage-matched wild type (A, C, E, G, I, K) and mutant (B, D, F, H, J, L) embryos. Furthermore, expression of vegfaa, the pro-angiogenic signal for ISV angiogenesis, persists in the ventral somites through the time-point after which apoptosis has resolved in LA1908 mutant embryos (K, L), whereas putative CVP pro-angiogenic signals in the ventral tail, bmp2b and bmp4, are absent from the ventral tail after one day of development (C, D, G, H), possibly explaining the differential ability of CVP versus ISV angiogenesis to recover after initial delay.

Expression Data

Genes:	bmp2b bmp4 vegfaa
Fish:	la116Tg utp15^{la1908/la1908}; la116Tg
Anatomical Terms:	somite ventral region tail bud ventral region
Stage Range:	20-25 somites to Prim-25

Expression Detail

Antibody Labeling

Phenotype Data

Phenotype Detail

Acknowledgments

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