ZFIN ID: ZDB-FIG-111018-24
Mouillesseaux et al., 2011 - Mutation in utp15 Disrupts Vascular Patterning in a p53-Dependent Manner in Zebrafish Embryos. PLoS One   6(9):e25013 Full text @ PLoS One
ADDITIONAL FIGURES
EXPRESSION / LABELING:
Genes:
Fish:
Anatomical Terms:
Stage Range: 14-19 somites to 20-25 somites
PHENOTYPE:
Fish:
Observed In:
Stage Range: 14-19 somites to 20-25 somites

Fig. S1 Gene expression in LA1908 is not globally disrupted. A–D, Markers of neural (krox20, A, B) and hematopoietic (cmyb, C, D) differentiation were indistinguishable between wild type and mutant embryos. n = 20 embryos for each condition. E–F, Development was not generally delayed, as somite number was not significantly different between LA1908 mutant and wild type siblings (E). Rather, delay was specific to vascular tissues, exemplified by decreased ISV number in mutant versus wild type embryos at 21 hpf (F). Ten embryos were analyzed per condition. NS = not significantly different, * = p<0.00005.

Gene Expression Details
Gene Antibody Fish Conditions Stage Anatomy Assay
egr2b la116Tg standard conditions 14-19 somites rhombomere 3 ISH
14-19 somites rhombomere 5 ISH
utp15la1908/la1908; la116Tg standard conditions 14-19 somites rhombomere 3 ISH
14-19 somites rhombomere 5 ISH
myb la116Tg standard conditions 20-25 somites intermediate cell mass of mesoderm ISH
utp15la1908/la1908; la116Tg standard conditions 20-25 somites intermediate cell mass of mesoderm ISH
Antibody Labeling Details No data available
Phenotype Details
Fish Conditions Stage Phenotype
utp15la1908/la1908; la116Tg standard conditions 14-19 somites neuron differentiation process quality, normal
20-25 somites hemopoiesis process quality, normal
20-25 somites intersegmental vessel decreased amount, abnormal
20-25 somites somite normal amount, normal
Acknowledgments:
ZFIN wishes to thank the journal PLoS One for permission to reproduce figures from this article. Please note that this material may be protected by copyright. Full text @ PLoS One