| ZFIN ID: ZDB-FIG-110909-74 |
Rothschild et al., 2011
- CaMK-II is a PKD2 target that promotes pronephric kidney development and stabilizes cilia.
Development (Cambridge, England)
138(16):3387-97
Full text @ Development
EXPRESSION / LABELING:
| Genes: | |
|---|---|
| Fish: | |
| Knockdown Reagent: | |
| Anatomical Terms: | |
| Stage Range: | 14-19 somites to Long-pec |
PHENOTYPE:
| Fish: | |
|---|---|
| Knockdown Reagent: | |
| Observed In: | |
| Stage: | Long-pec |
Fig. 6 Pronephros specification in camk2g1 morphants. Whole mount in situ hybridization of control and camk2g1 morphants using (A,B) pax2a at 14 somites (dorsal view), (C,D) cdh17, (E,F) gata3, (G,H) ret1 at 24 hpf (C-H, lateral view, anterior to the left); (I-L) wt1a at 24 hpf and 48 hpf (dorsal views). |
Gene Expression Details
| Gene | Antibody | Fish | Conditions | Stage | Anatomy | Assay |
|---|---|---|---|---|---|---|
| cdh17 | WT | control | Prim-5 | pronephric duct | ISH | |
| WT + MO1-camk2g1 | standard conditions | Prim-5 | pronephric duct | ISH | ||
| gata3 | WT | control | Prim-5 | pronephric duct distal region | ISH | |
| WT + MO1-camk2g1 | standard conditions | Prim-5 | pronephric duct distal region | ISH | ||
| pax2a | WT | control | 14-19 somites | intermediate mesoderm | ISH | |
| WT + MO1-camk2g1 | standard conditions | 14-19 somites | intermediate mesoderm | ISH | ||
| ret | WT | control | Prim-5 | pronephric duct distal region | ISH | |
| WT + MO1-camk2g1 | standard conditions | Prim-5 | pronephric duct distal region | ISH | ||
| wt1a | WT | control | Prim-5 | pronephric podocyte | ISH | |
| Long-pec | pronephric podocyte | ISH | ||||
| WT + MO1-camk2g1 | standard conditions | Prim-5 | pronephric podocyte | ISH | ||
| Long-pec | pronephric podocyte | ISH |
Antibody Labeling Details
No data available
Phenotype Details
| Fish | Conditions | Stage | Phenotype |
|---|---|---|---|
| WT + MO1-camk2g1 | standard conditions | Long-pec | pronephric podocyte unfused from pronephric podocyte, abnormal |
| Acknowledgments: | ZFIN wishes to thank the journal Development (Cambridge, England) for permission to reproduce figures from this article. Please note that this material may be protected by copyright. Full text @ Development |
|---|