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ZIRC
ZFIN ID: ZDB-GENE-980526-307
Gene Name: ret proto-oncogene receptor tyrosine kinase
Gene Symbol: ret
Sequence Ontology ID : SO:0000704

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Previous Names: c-ret (1), cret, etID315074.13 (1), ret1, wu:fd13h01

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(Including Attributions)
Location: Chr: 13 Mapping Details/Browsers
Nomenclature History
AUTOMATED DESCRIPTION
Exhibits protein homodimerization activity. Involved in several processes, including autonomic nervous system development; branchiomeric skeletal muscle development; and protein-containing complex  ...
DISEASE ASSOCIATED WITH ret HUMAN ORTHOLOG
Disease Ontology Term OMIM Term OMIM Phenotype ID
congenital central hypoventilation syndrome Central hypoventilation syndrome, congenital 209880
familial medullary thyroid carcinoma Medullary thyroid carcinoma 155240
multiple endocrine neoplasia type 2A Multiple endocrine neoplasia IIA 171400
multiple endocrine neoplasia type 2B Multiple endocrine neoplasia IIB 162300
pheochromocytoma Pheochromocytoma 171300
{Hirschsprung disease, protection against} 142623
{Hirschsprung disease, susceptibility to, 1} 142623
DISEASE ASSOCIATED WITH ret VIA EXPERIMENTAL MODELS
Human Disease Fish Conditions Citations
Hirschsprung's disease rethu2846/+ standard conditions Heanue et al., 2016
GENE ONTOLOGY
Ontology GO Term
Biological Process protein-containing complex assembly (more)
Cellular Component membrane (more)
Molecular Function protein binding (more)
GO Terms (all 31)
TRANSCRIPTS
Type Name Length (bp) Analysis
mRNA ret-201 (1) 4230
ret-202 (1) 5094
GENE PRODUCT DESCRIPTION
INTERACTIONS AND PATHWAYS
ANTIBODIESNo data available
PLASMIDSNo data available
CONSTRUCTS WITH SEQUENCES FROM ret
MARKER RELATIONSHIPS
retContained in: [BAC] DKEY-192P21 (1) (order this)
retEncodes: [EST] fd13h01
SEQUENCE INFORMATION
Type Accession # Length (bp/aa) Analysis
RNA RefSeq:NM_181662 (1) 4145bp
Genomic GenBank:AC124155 (1) 173037bp
Select Tool
Polypeptide UniProtKB:A8E7C6 (1) 1106aa
Sequence Clusters UniGene:75763 (1)
Sequence Information (all 24)
ORTHOLOGY for ret (Chr: 13)
CITATIONS (89)