FIGURE

Fig. 7

ID

ZDB-FIG-110811-50

Publication

Webb et al., 2011 - The Enhancer of split transcription factor Her8a is a novel dimerisation partner for Her3 that controls anterior hindbrain neurogenesis in zebrafish

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Fig. 7

her8a expression in the early neural plate is partially dependent on the expression of SoxB factors. Dorsal views of flat-mounted embryos analyzed at the 5-somite stage (A-F) and 3-somite stage (G-H) for the expression of the genes indicated (color-coded). A-F. her8a expression overlaps with that of the Sox family members sox2, sox3, sox19a, sox19b and sox21a, including the mid- and anterior hindbrain (red brackets). G-I. the simultaneous knockdown of sox2/3/19a/19b and 21a causes a reduction of her8a expression in the MH area of the early neural plate (white arrows).

Expression Data

Genes:	her8a sox2 sox3 sox19a sox19b sox21a
Fish:	WT WT + MO3-sox19a + MO3-sox19b + MO3-sox21a + MO5-sox2,sox3
Knockdown Reagents:	MO3-sox19a MO3-sox19b MO3-sox21a MO5-sox2,sox3
Anatomical Terms:	hindbrain neural keel anterior region midbrain hindbrain boundary neural plate midbrain neural keel midbrain neural rod presumptive diencephalon ventral region presumptive rhombomere 3 presumptive telencephalon
Stage Range:	1-4 somites to 5-9 somites

Expression Detail

Antibody Labeling

Phenotype Data

Fish:	WT + MO3-sox19a + MO3-sox19b + MO3-sox21a + MO5-sox2,sox3
Knockdown Reagents:	MO3-sox19a MO3-sox19b MO3-sox21a MO5-sox2,sox3
Observed In:	hindbrain neural keel midbrain hindbrain boundary neural keel midbrain neural keel
Stage:	1-4 somites

Phenotype Detail

Acknowledgments

This image is the copyrighted work of the attributed author or publisher, and ZFIN has permission only to display this image to its users. Additional permissions should be obtained from the applicable author or publisher of the image. Full text @ BMC Dev. Biol.