Gene

her8a

ID

ZDB-GENE-030131-2376

Name

hairy-related 8a

Symbol

her8a Nomenclature History

Previous Names

her8b (1)
wu:fb75f05 (1)
wu:fc06c04 (1)
zgc:85712 (1)

Type

protein_coding_gene

Location

Chr: 7 Mapping Details/Browsers

Description

Exhibits DNA-binding transcription factor activity, RNA polymerase II-specific. Involved in gliogenesis; negative regulation of neurogenesis; and negative regulation of transcription by RNA polymerase II. Localizes to chromatin. Is expressed in several structures, including anterior neural keel; anterior neural rod; central nervous system; neural tube; and posterior neural keel.

Genome Resources

Note

None

Comparative Information

Expression

All Expression Data

19 figures from 8 publications

Cross-Species Comparison

High Throughput Data

GEO (1)

Expression Atlas

UO scRNA-seq (UCSC browser)

Single Cell Expression Atlas

Daniocell

Thisse Expression Data

MGC:85712 (17 images)

Wild Type Expression Summary

Phenotype

All Phenotype Data: 3 figures from 2 publications
Cross-Species Comparison: Alliance

Phenotype Summary

Mutations

Mutants

Sequence Targeting Reagents

Human Disease

Associated With her8a Human Ortholog

No data available

Associated With her8a Via Experimental Models

No data available

Gene Ontology

Protein Domains

Domain, Family, and Site Summary

Type	InterPro ID	Name
Domain	IPR003650	Orange domain
Domain	IPR011598	Myc-type, basic helix-loop-helix (bHLH) domain
Family	IPR050370	Hairy and Enhancer of Split/HEY-related
Homologous_superfamily	IPR036638	Helix-loop-helix DNA-binding domain superfamily