FIGURE
Fig. 5
Fig. 5
Smad2/3 exert their effects on neural development partially depending on Chd. Embryos were injected at the one-cell stage with an mRNA species or chd-MO as indicated, and examined for the expression of chd (A–H), sox2 (I–L) and gata2 (M–P) at the shield stage as well as for the expression of otx2/hoxb1b at the 90% epiboly stage (Q–T and Q′–T′). Orientations of embryos: dorsal views with animal pole to the top (A–H and Q–T); animal-pole views with dorsal to the right (M–P); and lateral views with dorsal to the right (I–L and Q′–T′). |
Expression Data
| Genes: | |
|---|---|
| Fish: | |
| Knockdown Reagent: | |
| Anatomical Terms: | |
| Stage Range: | Shield to 90%-epiboly |
Expression Detail
Antibody Labeling
Phenotype Data
Phenotype Detail
Acknowledgments
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Reprinted from Developmental Biology, 333(2), Jia, S., Wu, D., Xing, C., and Meng, A., Smad2/3 activities are required for induction and patterning of the neuroectoderm in zebrafish, 273-284, Copyright (2009) with permission from Elsevier. Full text @ Dev. Biol.