header logo image header logo text
Downloads Login
Research
General Information
ZIRC
ZFIN ID: ZDB-GENE-980526-290
Gene Name: homeobox B1b
Gene Symbol: hoxb1b    Nomenclature History

{{control.fieldName}} Edit

ID: {{control.nomenID}}
{{control.fieldName}}:
Reason:
Comments:

Attributions

{{pub.zdbID}}
Previous Names: Hoxa-1, hoxa1, cb249 (1), id:ibd5001 (1)

Add new Alias

Alias
Attribution

Attributions for Alias: {{control.newAlias}}

{{pub.zdbID}}

Delete Alias:

(Including Attributions)
Gene Type: protein_coding_gene
Location: Chr: 12 Mapping Details/Browsers
Description: Exhibits sequence-specific DNA binding activity. Involved in several processes, including hindbrain development; neural keel formation; and regulation of histone modification. Predicted to localize to the nucleus. Is expressed in several structures, including germ ring; mesoderm; neural keel; neural plate; and presumptive neural plate. Orthologous to human HOXB1 (homeobox B1).
Genome Resources: Alliance (1),  Gene:30374 (1),  Ensembl(GRCz11):ENSDARG00000054033 (1)
MUTATIONS AND SEQUENCE TARGETING REAGENTS
Allele Type Localization Consequence Mutagen Suppliers
b1219 Point Mutation Exon 1 Premature Stop ENU
fh095 Point Mutation Unknown Unknown ENU
fh286 Point Mutation Unknown Unknown ENU
hoxb1b_unrecovered Point Mutation Unknown Unknown ENU
tud17Gt Transgenic Insertion 5' UTR Unknown DNA
ua1006 Insertion Unknown Unknown TALEN
um195 Small Deletion Exon 1 Unknown ZINC_FINGER_NUCLEASE
um196 Indel Exon 1 Unknown ZINC_FINGER_NUCLEASE
um197 Indel Exon 1 Unknown ZINC_FINGER_NUCLEASE
Sequence Targeting Reagents
Targeting Reagent Created Alleles Publications
MO1-hoxb1b N/A 8
MO2-hoxb1b N/A 2
TALEN1-hoxb1b 1
DISEASE ASSOCIATED WITH hoxb1b HUMAN ORTHOLOG
Disease Ontology Term Multi-Species Data OMIM Term OMIM Phenotype ID
Facial paresis, hereditary congenital, 3 614744
DISEASE ASSOCIATED WITH hoxb1b VIA EXPERIMENTAL MODELS No data available
GENE ONTOLOGY
Ontology GO Term
Biological Process nucleosome organization (more)
Cellular Component nucleus (more)
Molecular Function sequence-specific DNA binding (more)
GO Terms (all 17)
TRANSCRIPTS
Type Name Length (nt) Analysis
mRNA hoxb1b-001 (1) 1310
hoxb1b-201 (1)    Ensembl 1606
Browsers: UCSCNCBIEnsemblZFIN
INTERACTIONS AND PATHWAYS
ANTIBODIES No data available
CONSTRUCTS WITH SEQUENCES FROM hoxb1b
Construct Regulatory Regions Coding Sequences Species Tg Lines Publications
Tg1(hsp70l:hoxb1b-EGFP) hsp70l EGFPhoxb1b Danio rerio 1 2
Tg2(hsp70l:hoxb1b-EGFP) hsp70l EGFPhoxb1b Danio rerio 1 2
MARKER RELATIONSHIPS
hoxb1b Contained in: [BAC] DKEY-11C5 (1) (order this)
[PAC] BUSM1-227H09 (2) (order this)
hoxb1b Encodes: [EST] cb249 (1) (order this), ibd5001 (1) (order this)
[cDNA] MGC:162122 (1) (order this)
SEQUENCE INFORMATION
Type Accession # Length (bp/aa) Analysis
RNA RefSeq:NM_131142 (1) 1628 bp
Genomic GenBank:BX001014 (1) 193523 bp
Select Tool
Polypeptide UniProtKB:A3KNJ6 (1) 307 aa
Sequence Clusters UniGene:117296 (1)
Sequence Information (all 36)
ORTHOLOGY for hoxb1b ( Chr: 12 )
CITATIONS (145)