FIGURE

Fig. S9

ID

ZDB-FIG-090710-79

Publication

Aanstad et al., 2009 - The Extracellular Domain of Smoothened Regulates Ciliary Localization and Is Required for High-Level Hh Signaling

Other Figures

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Fig. S9

Laterality defects in cilia knock-down embryos.
In situ hybridization for myocardial marker cmlc2 at 28hpf. In uninjected control embryos, 100% of hearts jogged to the left (A). In 33 – 65% of embryos injected with dnKif3b mRNA, qilin MO1 or qilin MO2, the heart jogged to the right (B) or remained in the midline (C). The table shows the percentage and total number of embryos counted showing left-sided hearts and midline or right-sided hearts for uninjected control embryos and embryos injected with either 200 pg dnKif3b mRNA, 5 ng qilin MO1, or 15ng qilin MO2.

Expression Data

Gene:	myl7
Fish:	WT WT + MO1-cluap1 WT + MO2-cluap1
Knockdown Reagents:	MO1-cluap1 MO2-cluap1
Anatomical Term:	heart tube
Stage:	Prim-5

Expression Detail

Antibody Labeling

Phenotype Data

Fish:	WT + MO1-cluap1 WT + MO2-cluap1
Knockdown Reagents:	MO1-cluap1 MO2-cluap1
Observed In:	determination of left/right symmetry heart tube
Stage:	Prim-5

Phenotype Detail

Acknowledgments

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