FIGURE

Fig. 2

ID
ZDB-FIG-070117-6
Publication
Jeong et al., 2007 - Patterning the zebrafish diencephalon by the conserved zinc-finger protein Fezl
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Fig. 2

Reduced fezl activity results in a deficit of the prethalamus. (A,B) Severe deficit of dlx2a in the prethalamus of a 28-hpf fezl morphant. Insets in A,B show unaffected dlx2a expression in the pharyngeal arch (pa) area. Arrow in A indicates dlx2a-expressing prethalamic cells; arrowhead in A indicates dlx2a-expressing hypothalamic cells. (C,D) Reduction of lhx5 in the prethalamic region of the fezl morphant. Arrows in C,D indicate lhx5-expressing prethalamic cells; arrowhead in C,D indicates lhx5-expressing posterior tubercular cells. (E-J) Expression of foxg1 in the telencephalon (E-F), nk2.1a in the hypothalamus (G-H) and six3b in the eye and optic stalk (I-J) are largely normal in fezl morphants. (K-N) Reduction of dlx2a and lhx5 expressions in 16-somite (16s) fezl morphants. Arrows in K,L indicate the telencephalon and prospective diencephalon; arrow in M,N indicates the prospective diencephalon. All are lateral views with specific stages and marker identities indicted in each panel. di, prospective diencephalon; hy, hypothalamus; pt, prethalamus; tel, telencephalon; os, optic stalk.

Expression Data
Genes:
Fish:
Knockdown Reagent:
Anatomical Terms:
Stage Range: 14-19 somites to Prim-5

Expression Detail
Antibody Labeling
Phenotype Data

Phenotype Detail
Acknowledgments
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