Gene

foxg1a

ID

ZDB-GENE-990415-267

Name

forkhead box G1a

Symbol

foxg1a Nomenclature History

Previous Names

BF-1
bf1
foxg1
brain factor 1
zgc:109850

Type

protein_coding_gene

Location

Chr: 17 Mapping Details/Browsers

Description

Predicted to have DNA-binding transcription factor activity and sequence-specific DNA binding activity. Involved in embryonic retina morphogenesis in camera-type eye; neuron differentiation; and nose development. Predicted to localize to nucleus. Is expressed in several structures, including anterior neural keel; immature eye; nervous system; neuroectoderm; and presumptive telencephalon. Orthologous to human FOXG1 (forkhead box G1).

Genome Resources

Note

None

Comparative Information

Expression

All Expression Data

55 figures from 33 publications

Cross-Species Comparison

High Throughput Data

GEO (1)

Expression Atlas

UO scRNA-seq (UCSC browser)

Single Cell Expression Atlas

Daniocell

Thisse Expression Data

No data available

Wild Type Expression Summary

Phenotype

All Phenotype Data: 7 figures from 4 publications
Cross-Species Comparison: Alliance

Phenotype Summary

Mutations

Mutants

Sequence Targeting Reagents

Human Disease

Associated With foxg1a Human Ortholog

Disease Ontology Term	Multi-Species Data	OMIM Term	OMIM Phenotype ID
Rett syndrome	Alliance	Rett syndrome, congenital variant	613454

Associated With foxg1a Via Experimental Models

No data available

Gene Ontology

Protein Domains

Domain, Family, and Site Summary

Type	InterPro ID	Name
Conserved_site	IPR018122	Fork head domain conserved site1
Conserved_site	IPR030456	Fork head domain conserved site 2
Domain	IPR001766	Fork head domain
Family	IPR047208	Forkhead box protein G1
Homologous_superfamily	IPR036388	Winged helix-like DNA-binding domain superfamily
Homologous_superfamily	IPR036390	Winged helix DNA-binding domain superfamily