FIGURE

Fig. S2

ID

ZDB-FIG-060403-6

Publication

Hogan et al., 2006 - Specification of the Primitive Myeloid Precursor Pool Requires Signaling through Alk8 in Zebrafish

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Fig. S2

Expression of Markers of Myeloid and Endothelial Terminal Differentiation in lost-a-fin Mutants Markers of myeloid terminal differentiation were vastly reduced in lost-a-fin, but tie2 expression in differentiating vascular endothelial cells was normal. (A–D) The expression of l-plastin (24 hpf) (A) and myeloperoxidase (mpo) (30 hpf) (C) was vastly reduced in lost-a-fin mutants (B and D), mutant genotype was determined by the loss of the ventral tail fin. (E–H) The expression of tie2 (24 hpf) (E and G) was normal in lost-a-fin mutants (F and H), mutant genotype was determined by the loss of the ventral tail fin. All panels show lateral views except (G) and (H), which are dorsal views. Arrows in (E) and (F) and brackets in (G) and (H) indicate vascular staining. n > 30 progeny were analyzed in each experiment from crosses of known heterozygotes.

Expression Data

Genes:	lcp1 mpx tek
Fish:	WT acvr1l^gl2/gl2
Anatomical Terms:	blood vasculature macrophage mature neutrophil
Stage Range:	Prim-5 to Prim-15

Expression Detail

Antibody Labeling

Phenotype Data

Phenotype Detail

Acknowledgments

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