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General Information
ZIRC
ZFIN ID: ZDB-GENE-990415-56
Gene Name: TEK tyrosine kinase, endothelial
Gene Symbol: tek
Sequence Ontology ID : SO:0001217

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Previous Names: tie-2, tie2 (1)

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(Including Attributions)
Location: Chr: 5 Mapping Details/Browsers
Nomenclature History
AUTOMATED DESCRIPTION
Predicted to have transmembrane receptor protein tyrosine kinase activity. Involved in angiogenesis and heart development. Predicted to localize to the integral component of plasma membrane and  ...
MUTATIONS AND SEQUENCE TARGETING REAGENTS
Allele Type Localization Consequence Mutagen Suppliers
hu1667 Point Mutation Unknown Premature Stop
Targeting reagents:
DISEASE ASSOCIATED WITH tek HUMAN ORTHOLOG
Disease Ontology Term OMIM Term OMIM Phenotype ID
multiple cutaneous and mucosal venous malformations Venous malformations, multiple cutaneous and mucosal 600195
Glaucoma 3, primary congenital, E 617272
DISEASE ASSOCIATED WITH tek VIA EXPERIMENTAL MODELS No data available
GENE ONTOLOGY
Ontology GO Term
Biological Process angiogenesis (more)
Cellular Component cell junction (more)
Molecular Function ATP binding (more)
GO Terms (all 26)
TRANSCRIPTS
Type Name Length (bp) Analysis
mRNA tek-002 (1) 560
tek-202 (1) 3436
GENE PRODUCT DESCRIPTION
INTERACTIONS AND PATHWAYS
ANTIBODIES
PLASMIDS
Addgene
CONSTRUCTS WITH SEQUENCES FROM tek No data available
MARKER RELATIONSHIPS
tek Contained in: [BAC] DKEY-87D21 (1) (order this)
tek Encodes: [cDNA] MGC:195221 (1) (order this)
SEQUENCE INFORMATION
Type Accession # Length (bp/aa) Analysis
RNA RefSeq:NM_131461 (1) 3601 bp
Genomic GenBank:CU855580 (1) 50040 bp
Select Tool
Polypeptide UniProtKB:B3DJR6 (1) 1116 aa
Sequence Clusters UniGene:75820 (1)
Sequence Information (all 22)
ORTHOLOGY for tek ( Chr: 5 )
CITATIONS (93)