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Gene / Transcript
ZDB-GENE-030131-4334
atf1
Gene Name: activating transcription factor 1
Previous Names: wu:fc92c07, zgc:64099
Location: 6 Mapping Details/Browsers
Matching Text:
Abbreviation atf1
Gene atf1
Related Gene Symbol atf1
Orthologue ATF1......Atf1
Gene / Transcript
ZDB-TSCRIPT-090929-16987
atf1-201
Transcript Name: atf1-201
Previous Names: atf1-001
Location: 6 Mapping Details/Browsers
Matching Text:
Abbreviation atf1-201
Gene atf1
Marker Abbrev atf1-201
Related Gene Symbol atf1...atf1
Gene / Transcript
ZDB-TSCRIPT-240503-2241
atf1-202
Transcript Name: atf1-202
Matching Text:
Abbreviation atf1-202
Gene atf1
Marker Abbrev atf1-202
Related Gene Symbol atf1...atf1
Ontologies
GO:1990590
ATF1-ATF4 transcription factor complex
Definition: Transcription factor complex consisting of ATF1 and ATF4 subunits that is capable of binding to cAMP response element (CRE) (consensus: 5'-GTGACGT[AC][AG]-3') of the GRP78 (HSPA5) promoter. Involved in the ER stress response pathway.
Matching Text:
Abbreviation ATF1-ATF4 transcription factor complex
Definition Transcription factor complex consisting of ATF1 and ATF4 subunits that is capable of binding to cAMP response element (CRE) (consensus: 5'-GTGACGT[AC][AG]-3') of the GRP78 (HSPA5) promoter.
Ontologies
GO:1990243
atf1-pcr1 complex
Definition: A heterodimeric transcription factor complex composed of the bZIP proteins atf1 and pcr1. The heterodimer binds m26 sites (homologous to CRE).
Matching Text:
Abbreviation atf1-pcr1 complex
Definition A heterodimeric transcription factor complex composed of the bZIP proteins atf1 and pcr1. The heterodimer binds m26 sites (homologous to CRE).
Antibody
ZDB-ATB-200914-4
Ab1-atf1
Synonyms: Anti-ATF1 (phospho S63) antibody [EP1591(2)Y] (ab76085)
Host Organism: Rabbit
Type: monoclonal [IgG]
Sources: Abcam plc
Matching Text:
Abbreviation Ab1-atf1
Marker Abbrev Ab1-atf1
Alias Anti-ATF1 (phospho S63) antibody [EP1591(2)Y] (ab76085)
Gene / Transcript
ZDB-GENE-010226-1
gdnfa
Gene Name: glial cell derived neurotrophic factor a
Previous Names: gdnf
Location: 10 Mapping Details/Browsers
Matching Text:
Orthologue ...ATF1
Gene / Transcript
ZDB-GENE-110609-2
gdnfb
Gene Name: glial cell derived neurotrophic factor b
Previous Names: si:ch73-311f13.2
Location: 5 Mapping Details/Browsers
Matching Text:
Orthologue ...ATF1
Expression
atf1 expression in AB/TU + standard at Zygote:1-cell to Hatching:Pec-fin from Thisse et al., 2004 Fig. 1
Gene: atf1
Probe: MGC:64099
Conditions: standard conditions
Stage: Zygote:1-cell to Hatching:Pec-fin
Expression:
Fish: AB/TU
Matching Text:
Abbreviation atf1 expression in AB/TU from Thisse et al.
Gene atf1
Related Gene Symbol atf1...atf1
Zebrafish Gene atf1
Marker / Clone
ZDB-EST-000613-92
fc92c07
Synonyms: etID7278.6
Type: EST
Location: 6 Mapping Details/Browsers
Clone Encoded By Gene: atf1
Matching Text:
Gene atf1
Related Gene Symbol atf1...atf1
Marker / Clone
ZDB-CDNA-040425-1287
MGC:64099
Synonyms: FR304
Type: CDNA
Clone Encoded By Gene: atf1
Matching Text:
Gene atf1
Related Gene Symbol atf1...atf1
Figure
ZDB-FIG-050630-9720
Thisse et al., 2004 Fig. 1
Publication: Fast Release Clones: A High Throughput Expression Analysis
Caption: not spatially restricted
Matching Text:
Related Gene Symbol atf1
Zebrafish Gene atf1
Expression Observation atf1 expressed in unspecified
Marker / Clone
ZDB-BAC-090114-669
CH73-187P21
Type: BAC
Location: 6 Mapping Details/Browsers
Clone Contains Genes: atf1, dip2bb, si:ch73-187p21.1
Matching Text:
Gene ...atf1
Related Gene Symbol ...atf1......atf1
Marker / Clone
ZDB-BAC-070404-606
CH211-173N18
Type: BAC
Location: 6 Mapping Details/Browsers
Clone Contains Genes: atf1, scn8ab, tmt1a.1, si:ch211-173n18.5, tmt1a.2, tmt1a.3
Matching Text:
Gene ...atf1
Related Gene Symbol ...atf1......atf1
Publication
ZDB-PUB-070614-18
CREB activity modulates neural cell proliferation, midbrain-hindbrain organization and patterning in zebrafish
Authors: Dworkin, S., Heath, J.K., Dejong-Curtain, T.A., Hogan, B.M., Lieschke, G.J., Malaterre, J., Ramsay, R.G., and Mantamadiotis, T.
Journal: Dev. Biol. 2007
Abstract:
Neural stem/progenitor cells (NPCs) self-renew and differentiate, generating neuronal and non-neuronal (glial) cell lineages. Although a number of factors, including transcription factors, have been shown to be important in the regulation of NPC proliferation and differentiation, the precise molecular networks remain to be identified. The cAMP Response Element-Binding protein (CREB) is a transcription factor important for neuronal survival, differentiation and plasticity. Recent work suggests that CREB activation, via serine phosphorylation in the kinase inducible domain, is important for neurogenesis in the adult rodent brain. We sought to further investigate CREB function in neurogenesis, using the zebrafish (Danio rerio). Structural and functional analysis of the zebrafish CREB orthologue showed high conservation with mammalian CREB. Activated (phosphorylated) CREB (pCREB) was localised to all known proliferation zones in the adult zebrafish brain, including actively cycling cells. Furthermore, we found that modulating CREB activity during early zebrafish development caused significant defects in neural proliferation, midbrain-hindbrain organization and body patterning. These findings reveal broader and stage-specific physiological roles of CREB function during vertebrate neural development and proliferation.
Matching Text:
Gene ...atf1
Related Gene Symbol ...atf1
Construct
ZDB-TGCONSTRCT-220927-6
Tg(tal1:atf3-2A-EGFP)
Synonyms: Tg(tal1:atf3△zip-2AeGFP)
Note: This construct contains the coded protein of atf3△zip was the truncated form bereft of the C-terminal activation domain.
Matching Text:
Construct Name Tg(tal1:atf3-2A-EGFP)
Fish
ZDB-FISH-240110-20
zf3481Tg
Affected Genomic Region Line / Reagent Mutation Type Construct Parental Zygosity
zf3481Tg Transgenic insertion Tg(tal1:atf3-2A-EGFP) Unknown
Matching Text:
Construct Name Tg(tal1:atf3-2A-EGFP)
Construct
ZDB-TGCONSTRCT-140929-2
Tg(fabp10a:atf6-mCherry,myl7:EGFP)
Synonyms: Tg(fabp10:nAtf6-cherry; cmlc2:GFP)
Note: This construct contains the nuclear active form of atf6.
Matching Text:
Construct Name Tg(fabp10a:atf6-mCherry,myl7:EGFP)
Fish
ZDB-FISH-150901-20741
mss6aTg
Affected Genomic Region Line / Reagent Mutation Type Construct Parental Zygosity
mss6aTg Transgenic insertion Tg(fabp10a:atf6-mCherry,myl7:EGFP) Unknown
Matching Text:
Construct Name Tg(fabp10a:atf6-mCherry,myl7:EGFP)
Fish
ZDB-FISH-150901-28992
mss6cTg
Affected Genomic Region Line / Reagent Mutation Type Construct Parental Zygosity
mss6cTg Transgenic insertion Tg(fabp10a:atf6-mCherry,myl7:EGFP) Unknown
Matching Text:
Construct Name Tg(fabp10a:atf6-mCherry,myl7:EGFP)
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don't look at my debug output!
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