ZFIN ID: ZDB-GENE-990415-44

Gene Name:cytochrome P450, subfamily XXVIA, polypeptide 1
Gene Symbol: cyp26a1

Previous Names: wu:fb81e05(1) , P450RAI, cb24(1) , id:ibd5061(1) , etID42255.12(1) , gir, giraffe
Nomenclature History

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GENE EXPRESSION:(current status)

All expression data:	47 figure(s) from 30 publications
Directly submitted expression data:	6 figure(s) (61 images) from Thisse et al., 2001 [cb24]
	3 figure(s) (4 images) from Kudoh et al., 2001 [ibd5061]
Wild Type Stages, Structures:	Blastula:30%-epiboly (4.66h-5.25h) to Adult (90d-730d, breeding adult)
	anterior neural plate, endoderm ... (all 46)
Curated microarray expression:	GEO  (1)

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MUTANTS AND TARGETED KNOCKDOWNS:

Mutant line(s):   2 genotypes
Allele(s):   rw716

Phenotype: (current status)

Data:	2 figures from 2 publications
Observed in:	blood circulation, eye, pancreas, pancreas development, pectoral fin bud ... (all 8)

Knockdown reagents: MO1-cyp26a1 (1) ,   MO2-cyp26a1 (1) ,   MO3-cyp26a1 (1)

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GENE PRODUCTS:

Gene Ontology

Ontology	GO Term
Biological Process	response to chemical stimulus (more)
Cellular Component	endoplasmic reticulum (more)
Molecular Function	retinoic acid 4-hydroxylase activity (more)

All GO Terms (23)

Protein Families, Domains and Sites:

InterPro:IPR001128 (1) InterPro:IPR002401 (1) InterPro:IPR017972 (1)

PROSITE:PS00086 (1)

Pfam:PF00067 (1)

EC:1.14.-.- (1)

Gene Product Description

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CONSTRUCTS WITH SEQUENCE FROM cyp26a1:

Tg(cyp26a1:eYFP)

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SEGMENT (CLONE AND PROBE) RELATIONSHIPS:

cyp26a1 Contained in	[BAC] DKEY-185B14 (1)    (order this)
cyp26a1 Encodes	[EST] cb24 (1)    (order this) , fb81e05 (1)    (order this) , ibd5061 (1)    (order this) [cDNA] MGC:63750 (1)    (order this)

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SEQUENCE INFORMATION:

Type	Accession #	Length (bp/aa)	Analysis
RNA	RefSeq:NM_131146 (1)	1848 bp	- Select Tool - ZFIN BLAST NCBI BLAST Ensembl UCSC BLAT
Genomic	GenBank:BX323992 (1)	153572 bp	- Select Tool - MegaBLAST Ensembl
Polypeptide	UniProtKB:P79739 (1)	492 aa	- Select Tool - ZFIN BLAST Ensembl SIB BLAST
Sequence Clusters	UniGene:75754 (1)
All Sequence Information (14)

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OTHER  cyp26a1  GENE / MARKER PAGES:

Entrez Gene:30381 (1)

VEGA:OTTDARG00000020512 (1)

Ensembl(Zv8):ENSDARG00000033999 (1)

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MAPPING INFORMATION:

LG:  12  Details

View Map: Merged  Individual Panels

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ORTHOLOGY:

				Evidence
Species	Symbol	Chromosome (Position)	Accession #	AA	NT	CL
Zebrafish	cyp26a1	12
Human	CYP26A1	10 (q23-q24)	OMIM:602239 Entrez Gene:1592
Mouse	Cyp26a1	19 (syntenic)	MGI:1096359 Entrez Gene:13082
Orthology Details

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CITATIONS   (60)