ZFIN ID: ZDB-GENE-990415-44
Gene Name: cytochrome P450, family 26, subfamily A, polypeptide 1
Gene Symbol: cyp26a1
Previous Names: cb24 (1), etID42255.12 (1), gir, giraffe, id:ibd5061 (1), P450RAI, wu:fb81e05 (1)
Location: Chr: 12 Mapping Details/Browsers
Nomenclature History
GENE EXPRESSION
All Expression Data: 82 figures from 51 publications
Directly Submitted Expression Data: 6 figures (61 images) from Thisse et al., 2001 [cb24]
  3 figures (4 images) from Kudoh et al., 2001 [ibd5061]
Wild-type Stages, Structures: Zygote:1-cell (0.0h-0.75h) to Adult (90d-730d, breeding adult)
  anatomical structure, anterior lateral plate mesoderm, anterior neural plate, anterior presumptive neural plate (all 81) expand
Curated Microarray Expression: GEO (1)
MUTATIONS AND SEQUENCE TARGETING REAGENTS
Allele Type Localization Consequence Mutagen Suppliers
rw716 Point Mutation Unknown Unknown ENU
sa1738 Point Mutation Unknown Unknown ENU
  • Zebrafish International Resource Center (ZIRC) (order this)
  • Targeting reagents: MO1-cyp26a1 (1), MO2-cyp26a1 (1), MO3-cyp26a1 (1), MO4-cyp26a1 (1), MO5-cyp26a1 (1)
    PHENOTYPE
    Data: 3 figures from 3 publications
    Observed in: blood, blood circulation, eye, heart (all 12) expand
    DISEASE ASSOCIATED WITH cyp26a1 HUMAN ORTHOLOGNo data available
    GENE ONTOLOGY
    Ontology GO Term
    Biological Process cellular response to vitamin A (more)
    Cellular Component endoplasmic reticulum (more)
    Molecular Function retinoic acid 4-hydroxylase activity (more)
    GO Terms (all 72)
    PROTEIN FAMILIES, DOMAINS AND SITES
  • InterPro:IPR001128 (1)
  • InterPro:IPR002401 (1)
  • InterPro:IPR017972 (1)
  • PROSITE:PS00086 (1)
  • Pfam:PF00067 (1)
  • EC:1.14.13.- (1)
  • TRANSCRIPTS
    Type Name Length (bp) Analysis
    mRNA cyp26a1-001 (1) 1830
    cyp26a1-002 (1) 835
    GENE PRODUCT DESCRIPTION
    INTERACTIONS AND PATHWAYSNo data available
    ANTIBODIES
    Ab1-cyp26a1 (1)
    PLASMIDSNo data available
    CONSTRUCTS WITH SEQUENCES FROM cyp26a1
    Tg(cyp26a1-RARE_mut:EYFP), Tg(cyp26a1:EYFP), Tg(hsp70l:cyp26a1)
    SEGMENT (CLONE AND PROBE) RELATIONSHIPS
    cyp26a1Contained in: [BAC] DKEY-185B14 (1) (order this)
    cyp26a1Encodes: [EST] cb24 (1) (order this), fb81e05 (1) (order this), ibd5061 (1) (order this)
    [cDNA] MGC:63750 (1) (order this)
    SEQUENCE INFORMATION
    Type Accession # Length (bp/aa) Analysis
    RNA RefSeq:NM_131146 (1) 1848bp
    Genomic GenBank:BX323992 (1) 153572bp
    Select Tool
    Polypeptide UniProtKB:P79739 (1) 492aa
    Sequence Clusters UniGene:75754 (1)
    Sequence Information (all 18)
    OTHER cyp26a1 GENE PAGES
  • Gene:30381 (1)
  • VEGA:OTTDARG00000020512 (1)
  • Ensembl(GRCz10):ENSDARG00000033999 (1)
  • ORTHOLOGY for cyp26a1 (Chr: 12)
    Species Symbol Chromosome Accession # Evidence
    Human CYP26A1 10
  • Gene:1592
  • OMIM:602239
  • HGNC:2603
  • Amino acid sequence comparison (4)
    Conserved genome location (synteny) (3)
    Nucleotide sequence comparison (1)
    Mouse Cyp26a1 19
  • MGI:1096359
  • Gene:13082
  • Amino acid sequence comparison (2)
    Conserved genome location (synteny) (1)
    Nucleotide sequence comparison (1)
    Download Curated Orthology
    CITATIONS (126)