Research
General Information
ZIRC
ZFIN ID: ZDB-GENE-990415-44
Gene Name: cytochrome P450, family 26, subfamily A, polypeptide 1
Gene Symbol: cyp26a1
Previous Names: cb24 (1), P450RAI, etID42255.12 (1), gir, giraffe, id:ibd5061 (1), wu:fb81e05 (1)
Location: Chr: 12   Details
Nomenclature History
GENE EXPRESSION
All Expression Data: 62 figures from 43 publications
Directly Submitted Expression Data: 6 figures (61 images) from Thisse et al., 2001 [cb24]
  3 figures (4 images) from Kudoh et al., 2001 [ibd5061]
Wild-type Stages, Structures: Blastula:30%-epiboly (4.66h-5.25h) to Adult (90d-730d, breeding adult)
  anterior lateral plate mesoderm, anterior neural plate, cloaca, endoderm (all 49) expand
Curated Microarray Expression: GEO (1)
MUTANTS AND TARGETED KNOCKDOWNS
Mutant lines: 3 genotypes
Alleles: rw716, sa1738
Knockdown reagents: MO1-cyp26a1 (1), MO2-cyp26a1 (1), MO3-cyp26a1 (1), MO4-cyp26a1 (1), MO5-cyp26a1 (1)
PHENOTYPE
Data: 3 figures from 3 publications
Observed in: blood, blood circulation, eye, heart (all 12) expand
GENE ONTOLOGY
Ontology GO Term
Biological Process cellular response to vitamin A (more)
Cellular Component endoplasmic reticulum (more)
Molecular Function retinoic acid 4-hydroxylase activity (more)
GO Terms (all 63)
PROTEIN FAMILIES, DOMAINS AND SITES
  • InterPro:IPR001128 (1)
  • InterPro:IPR002401 (1)
  • InterPro:IPR017972 (1)
  • PROSITE:PS00086 (1)
  • Pfam:PF00067 (1)
  • EC:1.14.-.- (1)
  • TRANSCRIPTS
    Type Name Length (bp) Analysis
    mRNA cyp26a1-001 (1) 1830
    cyp26a1-002 (1) 835
    GENE PRODUCT DESCRIPTION
    ANTIBODIES
    Ab1-cyp26a1 (1)
    CONSTRUCTS WITH SEQUENCES FROM cyp26a1
    Tg(cyp26a1-RARE_mut:EYFP), Tg(cyp26a1:eYFP), Tg(hsp70l:cyp26a1)
    SEGMENT (CLONE AND PROBE) RELATIONSHIPS
    cyp26a1 Contained in: [BAC] DKEY-185B14 (1)
    cyp26a1 Encodes: [EST] cb24 (1) (order this), fb81e05 (1), ibd5061 (1) (order this)
    [cDNA] MGC:63750 (1) (order this)
    SEQUENCE INFORMATION
    Type Accession # Length (bp/aa) Analysis
    RNA RefSeq:NM_131146 (1) 1848 bp
    Genomic GenBank:BX323992 (1) 153572 bp
    Select Tool
    Polypeptide UniProtKB:P79739 (1) 492 aa
    Sequence Clusters UniGene:75754 (1)
    Sequence Information (all 18)
    OTHER cyp26a1 GENE PAGES
  • Gene:30381 (1)
  • VEGA:OTTDARG00000020512 (1)
  • Ensembl(Zv9):ENSDARG00000033999 (1)
  • ORTHOLOGY
      Evidence
    Species Symbol Chr (Position) Accession # AA NT CL
    Zebrafish cyp26a1 12  
    Human CYP26A1 10 (10q23-q24)
  • OMIM:602239
  • Gene:1592
  • Mouse Cyp26a1 19 ( 32.36 cM)
  • MGI:1096359
  • Gene:13082
  • Orthology Details
    CITATIONS (101)