| ZFIN ID: ZDB-GENE-980526-41 |
| Gene Name: | sonic hedgehog b |
|---|---|
| Gene Symbol: | shhb |
| Previous Names: | twh, twhh, tiggy winkle hedgehog |
| Nomenclature History | |
| All Expression Data: | 41 figures from 30 publications |
| Directly Submitted Expression Data: | 7 figures (30 images) from Thisse et al., 2005 [eu390] |
| Wild-type Stages, Structures: | Blastula:256-cell (2.5h-2.75h) to Adult (90d-730d, breeding adult) |
|---|---|
axis,
diencephalon,
endoderm,
floor plate
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| Curated Microarray Expression: | GEO (1) |
| Alleles: | la023573Tg, la028783Tg |
| Knockdown reagents: | MO1-shhb (1), MO2-shhb (1), MO3-shhb (1), MO4-shhb (1) |
| Data: | text only from Hammond et al., 2003 |
| Observed in: | blood circulation, somite |
| Phenotype of Human Orthologue | OMIM Phenotype ID |
|---|---|
| Holoprosencephaly-3 | 142945 |
| Microphthalmia with coloboma 5 | 611638 |
| Schizencephaly | 269160 |
| Single median maxillary central incisor | 147250 |
| Ontology | GO Term |
|---|---|
| Biological Process | embryonic neurocranium morphogenesis (more) |
| Cellular Component | extracellular region (more) |
| Molecular Function | hydrolase activity (more) |
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| Et(shhb:Gal4TA4,UAS:mCherry), Et(shhb:KalTA4,UAS-E1b:mCherry), Tg(-5.2shhb:GFP), Tg(shhb:Gal4TA4, 5xUAS:mRFP) |
| shhb Contained in: | [BAC] DKEY-265A7 (1) (order this) |
| shhb Encodes: |
[EST]
eu390 (1)
[cDNA] MGC:101003 (1) (order this) |
| Type | Accession # | Length (bp/aa) | Analysis |
|---|---|---|---|
| RNA | RefSeq:NM_131199 (1) | 1990 bp |
Select Tool
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| Genomic | GenBank:CS126484 (1) |
Select Tool
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| Polypeptide | UniProtKB:Q90419 (1) | 416 aa |
Select Tool
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| Sequence Clusters | UniGene:75752 (1) |
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| Chr: 2 Details | View Map: Merged Individual Panels |
| Evidence | ||||||
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| Species | Symbol | Chromosome (Position) | Accession # | AA | CL | |
| Zebrafish | shhb | 2 |
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| Human | SHH | 7 (7q36) |
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| Mouse | Shh | 5 ( 14.39) |
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