ZFIN ID: ZDB-GENE-980526-285
Gene Name: cathepsin Lb
Gene Symbol: ctslb
Sequence Ontology ID : SO:0000704

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Previous Names: catL, cstlb (1), ctsl1b, ctsl, cathepsin L, cb15 (1), hatching gland 1 (1), hgg1 (1), wu:fb30g09 (1)

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(Including Attributions)
Location: Chr: 12 Mapping Details/Browsers
Nomenclature History
Note: This sequence is in a cluster of genes on chromosome 12 that may or may not be tandem duplicates of cstl.
GENE EXPRESSION
All Expression Data: 145 figures from 97 publications
Directly Submitted Expression Data: 11 figures (28 images) from Rauch et al., 2003 [fc13c06]
  6 figures (8 images) from Thisse et al., 2001 [cb15]
Wild-type Stages, Structures: Blastula:128-cell (2.25h-2.5h) to Larval:Day 5 (120.0h-144.0h, 3.9mm, 6 teeth)
  anterior axial hypoblast, axial chorda mesoderm, axial mesoderm, ectoderm (all 16) expand
Curated Microarray Expression: GEO (1)
MUTATIONS AND SEQUENCE TARGETING REAGENTS
Allele Type Localization Consequence Mutagen Suppliers
sa22068 Point Mutation Unknown Splice Site ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • Zebrafish International Resource Center (ZIRC) (order this)
  • sa27926 Point Mutation Unknown Premature Stop ENU
    PHENOTYPE No data available
    DISEASE ASSOCIATED WITH ctslb HUMAN ORTHOLOGNo data available
    GENE ONTOLOGY
    Ontology GO Term
    Biological Process proteolysis (more)
    Cellular Component extracellular region (more)
    Molecular Function cysteine-type peptidase activity (more)
    GO Terms (all 9)
    PROTEIN FAMILIES, DOMAINS AND SITES
  • InterPro:IPR000169 (1)
  • InterPro:IPR000668 (1)
  • InterPro:IPR013128 (1)
  • InterPro:IPR013201 (1)
  • InterPro:IPR025660 (1)
  • InterPro:IPR025661 (1)
  • PROSITE:PS00139 (1)
  • PROSITE:PS00639 (1)
  • PROSITE:PS00640 (1)
  • Pfam:PF00112 (1)
  • Pfam:PF08246 (1)
  • TRANSCRIPTS
    Type Name Length (bp) Analysis
    mRNA ctslb-001 (1) 1351
    ctslb-002 (1) 308
    ottdart00000058084 (1) 1289
    ottdart00000058085 (1) 1348
    GENE PRODUCT DESCRIPTION
    INTERACTIONS AND PATHWAYS
    ANTIBODIESNo data available
    PLASMIDSNo data available
    CONSTRUCTS WITH SEQUENCES FROM ctslb No data available
    MARKER RELATIONSHIPS
    ctslbContained in: [BAC] DKEY-239J18 (1) (order this), DKEY-269I1 (1) (order this)
    ctslbEncodes: [EST] cb15 (1) (order this), fb30g09 (1), fc13c06 (1) (order this)
    [cDNA] MGC:123162 (1) (order this), MGC:174152 (1) (order this), MGC:174155 (1) (order this), MGC:174856 (1) (order this), MGC:174857 (1) (order this)
    SEQUENCE INFORMATION
    Type Accession # Length (bp/aa) Analysis
    RNA GenBank:BC108031 (1) 1320bp
    Genomic GenBank:BX322603 (1) 191741bp
    Select Tool
    Polypeptide UniProtKB:F1R7B3 (1) 352aa
    Sequence Information (all 18)
    OTHER ctslb GENE PAGES
  • Alliance (1)
  • VEGA:OTTDARG00000020540 (1)
  • VEGA:OTTDARG00000040457 (1)
  • VEGA:OTTDARG00000040458 (1)
  • Ensembl(GRCz10):ENSDARG00000074306 (1)
  • ORTHOLOGY for ctslb (Chr: 12)
    CITATIONS (192)