Gene

srsf2a

ID
ZDB-GENE-040426-2706
Name
serine and arginine rich splicing factor 2a
Symbol
srsf2a Nomenclature History
Previous Names
  • sfrs2
  • srsf2
  • hm:zeh0252
  • wu:fb51a05
  • wu:fk59b08
  • zgc:56283
Type
protein_coding_gene
Location
Chr: 12 Mapping Details/Browsers
Description
Predicted to have RNA binding activity. Predicted to be involved in mRNA cis splicing, via spliceosome and regulation of alternative mRNA splicing, via spliceosome. Predicted to localize to cytoplasm and nuclear speck. Human ortholog(s) of this gene implicated in acute myeloid leukemia and myelodysplastic syndrome. Orthologous to several human genes including SRSF2 (serine and arginine rich splicing factor 2).
Genome Resources
Note
None
Expression
All Expression Data
2 figures from 2 publications
Cross-Species Comparison
High Throughput Data
No data available
Wild Type Expression Summary
Phenotype
All Phenotype Data
No data available
Cross-Species Comparison
Alliance
Phenotype Summary
Mutations
Mutants
Sequence Targeting Reagents
Human Disease
Associated With srsf2a Human Ortholog
No data available
Associated With srsf2a Via Experimental Models
No data available
Gene Ontology
Protein Domains
Domain, Family, and Site Summary
Type InterPro ID Name
Domain IPR000504 RNA recognition motif domain
Domain IPR003954 RNA recognition motif domain, eukaryote
Family IPR034893 Serine/arginine-rich splicing factor 2-like
Homologous_superfamily IPR012677 Nucleotide-binding alpha-beta plait domain superfamily
Homologous_superfamily IPR035979 RNA-binding domain superfamily
Domain Details Per Protein
Protein Length Nucleotide-binding alpha-beta plait domain superfamily RNA-binding domain superfamily RNA recognition motif domain RNA recognition motif domain, eukaryote Serine/arginine-rich splicing factor 2-like
UniProtKB:U3JAJ1 85
UniProtKB:U3JAU8 47
UniProtKB:Q7ZV13 225
UniProtKB:U3JB26 118
UniProtKB:U3JA46 13
UniProtKB:U3JAM8 199
UniProtKB:E9QHD6 174
UniProtKB:U3JA80 148
Transcripts
Genome Browsers
Interactions and Pathways
No data available
Antibodies
No data available
Plasmids
No data available
Constructs
Marker Relationships
Sequences
Orthology
Ensembl Gene Tree
Citations