FIGURE

Fig. 5

ID
ZDB-FIG-230728-22
Publication
Lin et al., 2023 - YULINK regulates vascular formation in zebrafish and HUVECs
Other Figures
All Figure Page
Back to All Figure Page
Fig. 5

Effects of an endocytosis inhibitor on vein morphogenesis in vivo and capillary tube formation in vitro. A The double Tg (fli1:EGFP; gata1:DsRed) embryos were treated with endocytosis inhibitor, chlorpromazine (60 nM), at 16 hpf. Chlorpromazine was removed at 22 hpf. The lateral and cross-section views of blood vessels in trunk and tail of the Tg (fli1:EGFP; gata1:DsRed) embryos at 24 hpf were shown. White dotted lines indicate the position where the cross-sections are taken. The upper panels were shown as WT groups. DA dorsal aorta, PCV posterior cardinal vein, CA caudal artery, CV caudal vein. Scale bars indicate 50 μm. B Chlorpromazine-mediated inhibition of capillary tube formation in vitro. HUVECs were pretreated with different concentrations of chlorpromazine for 1 h and then seeded in 12-well plates coated with Matrigel. Representative areas are photographed at 10× magnification. Black scale bars indicate 400 μm. Data points represent mean ± SD of two replicate experiments with 4 measurements per treatment

Expression Data

Expression Detail
Antibody Labeling
Phenotype Data
Fish:
Condition:
Observed In:
Stage: Prim-5

Phenotype Detail
Acknowledgments
This image is the copyrighted work of the attributed author or publisher, and ZFIN has permission only to display this image to its users. Additional permissions should be obtained from the applicable author or publisher of the image. Full text @ Biol. Res.