FIGURE

Fig. 1

ID

ZDB-FIG-221226-304

Publication

Saettele et al., 2022 - Prolonged Dexamethasone Exposure Enhances Zebrafish Lateral-Line Regeneration But Disrupts Mitochondrial Homeostasis and Hair Cell Function

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Fig. 1

Workflow of CuSO₄ lateral-line lesion and dexamethasone exposure. A Diagram of workflow for CuSO₄ lesions and dexamethasone exposure. Larvae (5 dpf) were placed into cell strainers and moved between rinse and lesion steps, while being allowed to swim freely during recovery and dexamethasone exposure. B Diagram of a 5–7 dpf zebrafish larvae showing the distribution of lateral-line neuromasts (magenta) and innervating afferent nerves (green). This study focused on neuromasts L3, L4, and L5 (blue dashed-line box). C Representative maximum intensity projection of confocal z-stack image of neuromast L4 in a 7 dpf zebrafish larvae. Labels: afferent neurons labeled with GFP (green; tgBAC (neurod1: GFP), DAPI-labeled hair cell nuclei (blue), and immunolabeled presynaptic ribbons (magenta; pan-CtBP)

Expression Data

Expression Detail

Antibody Labeling

Phenotype Data

Phenotype Detail

Acknowledgments

This image is the copyrighted work of the attributed author or publisher, and ZFIN has permission only to display this image to its users. Additional permissions should be obtained from the applicable author or publisher of the image. Full text @ J. Assoc. Res. Otolaryngol.