ZFIN ID: ZDB-FIG-190627-53
So et al., 2017 - Wnt/β-catenin signaling controls intrahepatic biliary network formation in zebrafish by regulating Notch activity. Hepatology (Baltimore, Md.)   67(6):2352-2366 Full text @ Hepatology
ADDITIONAL FIGURES
EXPRESSION / LABELING:
Genes:
Fish:
Conditions:
Anatomical Terms:
Stage: Day 4
PHENOTYPE:
Fish:
Conditions:
Observed In:
Stage: Day 4

Fig. 4 ZFIN is incorporating published figure images and captions as part of an ongoing project. Figures from some publications have not yet been curated, or are not available for display because of copyright restrictions.

Gene Expression Details
Gene Antibody Fish Conditions Stage Anatomy Assay
axin2 WT chemical treatment by environment: XAV939 Day 4 whole organism RTPCR
s704Tg standard conditions Day 4 whole organism RTPCR
her2 WT control Day 4 liver ISH
WT chemical treatment by environment: XAV939 Day 4 liver ISH
Day 4 whole organism RTPCR
her9 WT control Day 4 liver ISH
WT chemical treatment by environment: XAV939 Day 4 liver ISH
Day 4 whole organism RTPCR
her15.1 WT control Day 4 liver ISH
WT chemical treatment by environment: XAV939 Day 4 liver ISH
Day 4 whole organism RTPCR
jag1b WT control Day 4 liver ISH
WT chemical treatment by environment: XAV939 Day 4 liver ISH
Day 4 whole organism RTPCR
s704Tg standard conditions Day 4 liver ISH
Day 4 whole organism RTPCR
jag2b WT control Day 4 liver ISH
WT chemical treatment by environment: XAV939 Day 4 liver ISH
Day 4 whole organism RTPCR
s704Tg standard conditions Day 4 liver ISH
Day 4 whole organism RTPCR
mCherry s939Tg; s940Tg control Day 4 intrahepatic bile duct epithelial cell IFL
s939Tg; s940Tg chemical treatment by environment: XAV939 Day 4 intrahepatic bile duct epithelial cell IFL
w35Tg ; s940Tg ; s939Tg heat shock Day 4 intrahepatic bile duct epithelial cell IFL
Venus s939Tg; s940Tg control Day 4 intrahepatic bile duct epithelial cell IFL
s939Tg; s940Tg chemical treatment by environment: XAV939 Day 4 intrahepatic bile duct epithelial cell IFL
w35Tg ; s940Tg ; s939Tg heat shock Day 4 intrahepatic bile duct epithelial cell IFL
Antibody Labeling Details No data available
Phenotype Details
Fish Conditions Stage Phenotype
WT chemical treatment by environment: XAV939 Day 4 liver her15.1 expression decreased amount, abnormal
Day 4 liver her2 expression decreased amount, abnormal
Day 4 liver her9 expression decreased amount, abnormal
Day 4 liver jag1b expression decreased amount, abnormal
Day 4 liver jag2b expression decreased amount, abnormal
Day 4 whole organism axin2 expression decreased amount, abnormal
Day 4 whole organism her15.1 expression decreased amount, abnormal
Day 4 whole organism her2 expression decreased amount, abnormal
Day 4 whole organism her9 expression decreased amount, abnormal
Day 4 whole organism jag1b expression decreased amount, abnormal
Day 4 whole organism jag2b expression decreased amount, abnormal
s704Tg standard conditions Day 4 liver jag1b expression increased amount, abnormal
Day 4 liver jag2b expression increased amount, abnormal
Day 4 whole organism axin2 expression increased amount, abnormal
Day 4 whole organism jag1b expression increased amount, abnormal
Day 4 whole organism jag2b expression increased amount, abnormal
s939Tg; s940Tg chemical treatment by environment: XAV939 Day 4 intrahepatic bile duct epithelial cell Notch signaling pathway decreased process quality, abnormal
Day 4 intrahepatic bile duct epithelial cell Venus expression decreased amount, abnormal
w35Tg ; s940Tg ; s939Tg heat shock Day 4 intrahepatic bile duct epithelial cell Notch signaling pathway decreased process quality, abnormal
Day 4 intrahepatic bile duct epithelial cell Venus expression decreased amount, abnormal
Full text @ Hepatology
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