Gene

jag2b

ID
ZDB-GENE-011128-3
Name
jagged canonical Notch ligand 2b
Symbol
jag2b Nomenclature History
Previous Names
  • jag2
  • jagged2
  • serB
  • serrateB
  • unp1068
  • zgc:152855
Type
protein_coding_gene
Location
Chr: 20 Mapping Details/Browsers
Description
Predicted to have Notch binding activity and calcium ion binding activity. Involved in animal organ development. Predicted to localize to plasma membrane and protein-containing complex. Is expressed in several structures, including anterior neural rod; digestive system; mesoderm; nervous system; and trunk. Orthologous to human JAG2 (jagged canonical Notch ligand 2).
Genome Resources
Note
None
Comparative Information
Expression
All Expression Data
41 figures from 28 publications
Cross-Species Comparison
High Throughput Data
Thisse Expression Data
Wild Type Expression Summary
Phenotype
All Phenotype Data
9 figures from 5 publications
Cross-Species Comparison
Alliance
Phenotype Summary
Mutations
Mutants
Sequence Targeting Reagents
Human Disease
Associated With jag2b Human Ortholog
Disease Ontology Term Multi-Species Data OMIM Term OMIM Phenotype ID
Muscular dystrophy, limb-girdle, autosomal recessive 27 619566
Associated With jag2b Via Experimental Models
No data available
Gene Ontology
Protein Domains
Domain, Family, and Site Summary
Type InterPro ID Name
Conserved_site IPR018097 EGF-like calcium-binding, conserved site
Domain IPR000742 EGF-like domain
Domain IPR001007 VWFC domain
Domain IPR001774 Delta/Serrate/lag-2 (DSL) protein
Domain IPR001881 EGF-like calcium-binding domain
Domain IPR011651 Notch ligand, N-terminal domain
Family IPR026219 Jagged/Serrate protein
Family IPR033108 Protein jagged-1
Homologous_superfamily IPR009030 Growth factor receptor cysteine-rich domain superfamily
PTM IPR000152 EGF-type aspartate/asparagine hydroxylation site
Domain Details Per Protein
Protein Length Delta/Serrate/lag-2 (DSL) protein EGF-like calcium-binding, conserved site EGF-like calcium-binding domain EGF-like domain EGF-type aspartate/asparagine hydroxylation site Growth factor receptor cysteine-rich domain superfamily Jagged/Serrate protein Notch ligand, N-terminal domain Protein jagged-1 VWFC domain
UniProtKB:Q90Y56 1254
UniProtKB:Q9YHU2 1254
UniProtKB:Q5TZK7 1216
UniProtKB:A0A2R8QT22 1216
UniProtKB:Q0P4F9 139
UniProtKB:A0A0R4IAF3 1254
UniProtKB:B3DKL2 1254
UniProtKB:Q90Y55 1216
UniProtKB:Q5TZK8 1254
Transcripts
Genome Browsers
Interactions and Pathways
Antibodies
No data available
Plasmids
No data available
Constructs
Marker Relationships
Sequences
Orthology
Comparative Orthology
Alliance
Gene Tree
Ensembl
Citations