ZFIN ID: ZDB-GENE-011128-3
Gene Name: jagged canonical Notch ligand 2b
Gene Symbol: jag2b    Nomenclature History

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Previous Names: jag2, jagged2, serB, serrateB, unp1068, zgc:152855

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(Including Attributions)
Gene Type: protein_coding_gene
Location: Chr: 20 Mapping Details/Browsers
Description: Predicted to have Notch binding activity and calcium ion binding activity. Involved in animal organ development. Predicted to localize to plasma membrane and protein-containing complex. Is expressed in several structures, including anterior neural rod; digestive system; mesoderm; nervous system; and trunk. Orthologous to human JAG2 (jagged canonical Notch ligand 2).
Genome Resources: Alliance (1),  Gene:140422 (1),  Ensembl(GRCz11):ENSDARG00000021389 (1)
MUTATIONS AND SEQUENCE TARGETING REAGENTS
Allele Type Localization Consequence Mutagen Suppliers
hu3425 Point Mutation Unknown Premature Stop ENU
ihb328 Indel Exon 23 Unknown CRISPR
ihb329 Indel Exon 2 Unknown CRISPR
ihb330 Small Deletion Exon 2 Unknown CRISPR
ihb331 Small Deletion Unknown Unknown CRISPR
ihb344 Indel Exon 2 Unknown CRISPR
sa1720 Point Mutation Unknown Splice Site ENU
  • Zebrafish International Resource Center (ZIRC) (order this)
  • sa6629 Point Mutation Unknown Splice Site ENU
    sa10420 Point Mutation Unknown Splice Site ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • Zebrafish International Resource Center (ZIRC) (order this)
  • sa10654 Point Mutation Unknown Premature Stop ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • Zebrafish International Resource Center (ZIRC) (order this)
  • sa13408 Point Mutation Unknown Splice Site ENU
  • Zebrafish International Resource Center (ZIRC) (order this)
  • sa23675 Point Mutation Unknown Splice Site ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • Zebrafish International Resource Center (ZIRC) (order this)
  • sa29338 Point Mutation Unknown Splice Site ENU
    sa45693 Point Mutation Unknown Splice Site ENU
  • Zebrafish International Resource Center (ZIRC) (order this)
  • Sequence Targeting Reagents
    Targeting Reagent Created Alleles Publications
    CRISPR1-jag2b 1
    CRISPR2-jag2b 1
    MO1-jag2b N/A 9
    MO2-jag2b N/A 2
    MO3-jag2b N/A 2
    MO4-jag2b N/A 1
    MO5-jag2b N/A 2
    MO6-jag2b N/A 2
    MO7-jag2b N/A 2
    MO8-jag2b N/A 2
    MO9-jag2b N/A 1
    MO10-jag2b N/A 1
    MO11-jag2b N/A 1
    DISEASE ASSOCIATED WITH jag2b HUMAN ORTHOLOG No data available
    DISEASE ASSOCIATED WITH jag2b VIA EXPERIMENTAL MODELS No data available
    GENE ONTOLOGY
    Ontology GO Term
    Biological Process exocrine pancreas development (more)
    Cellular Component integral component of membrane (more)
    Molecular Function calcium ion binding (more)
    GO Terms (all 18)
    PROTEIN FAMILIES, DOMAINS AND SITES No links to external sites available
    TRANSCRIPTS
    Type Name Length (nt) Analysis
    mRNA jag2b-201 (1)    Ensembl 5438
    jag2b-202 (1)    Ensembl 5324
    ncRNA jag2b-003 (1)    Ensembl 812
    Browsers: UCSCNCBIEnsemblZFIN
    INTERACTIONS AND PATHWAYS
    SignaFish
    ANTIBODIES No data available
    PLASMIDS No data available
    CONSTRUCTS WITH SEQUENCES FROM jag2b No data available
    MARKER RELATIONSHIPS
    jag2b Contained in: [BAC] CH211-194O4 (1), DKEY-5P1 (1) (order this)
    jag2b Encodes: [EST] af090432, eu1049 (1)
    [cDNA] cssl:d403 (1), MGC:152855 (1), MGC:195316 (1)
    SEQUENCE INFORMATION
    Type Accession # Length (nt/aa) Analysis
    RNA RefSeq:NM_131862 (1) 5469 nt
    Genomic GenBank:BX004766 (1) 214782 nt Blast at MegaBLAST
    Polypeptide UniProtKB:A0A0R4IAF3 (1) 1254 aa
    Sequence Information (all 38)
    ORTHOLOGY for jag2b ( Chr: 20 )
    CITATIONS (86)