ZFIN ID: ZDB-GENE-000403-2
Gene Name: axin 2 (conductin, axil)
Gene Symbol: axin2
Sequence Ontology ID : SO:0000704

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Previous Names: axil, etID37069.3 (1), wu:fb37c08 (1), zgc:111942

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(Including Attributions)
Location: Chr: 3 Mapping Details/Browsers
Nomenclature History
GENE EXPRESSION
All Expression Data: 59 figures from 42 publications
Directly Submitted Expression Data: 7 figures (27 images) from Thisse et al., 2004 [IMAGE:3818167]
  6 figures (19 images) from Thisse et al., 2005 [eu48]
Wild-type Stages, Structures: Blastula:Sphere (4.0h-4.33h) to Adult (90d-730d, breeding adult)
  anatomical structure, brain, brain dorsal region, central nervous system (all 37) expand
Curated Microarray Expression: GEO (1)
MUTATIONS AND SEQUENCE TARGETING REAGENTS
Allele Type Localization Consequence Mutagen Suppliers
sa40180 Point Mutation Unknown Premature Stop ENU
  • Zebrafish International Resource Center (ZIRC) (order this)
  • sa40181 Point Mutation Unknown Splice Site ENU
  • Zebrafish International Resource Center (ZIRC) (order this)
  • PHENOTYPE No data available
    DISEASE ASSOCIATED WITH axin2 HUMAN ORTHOLOG
    Disease Ontology Term OMIM Term OMIM Phenotype ID
    colorectal cancer Colorectal cancer, somatic 114500
    Oligodontia-colorectal cancer syndrome 608615
    GENE ONTOLOGY
    Ontology GO Term
    Biological Process dorsal/ventral pattern formation (more)
    Cellular Component cytoplasm (more)
    Molecular Function GTPase activator activity (more)
    GO Terms (all 8)
    PROTEIN FAMILIES, DOMAINS AND SITES
  • InterPro:IPR001158 (1)
  • InterPro:IPR014936 (1)
  • InterPro:IPR016137 (1)
  • InterPro:IPR024066 (1)
  • InterPro:IPR029071 (1)
  • InterPro:IPR032101 (1)
  • InterPro:IPR036305 (1)
  • InterPro:IPR038207 (1)
  • PROSITE:PS50132 (1)
  • PROSITE:PS50841 (1)
  • Pfam:PF00615 (1)
  • Pfam:PF00778 (1)
  • Pfam:PF08833 (1)
  • Pfam:PF16646 (1)
  • TRANSCRIPTS
    Type Name Length (bp) Analysis
    mRNA axin2-001 (1) 3515
    ncRNA axin2-002 (1) 1429
    GENE PRODUCT DESCRIPTION
    INTERACTIONS AND PATHWAYS
    ANTIBODIESNo data available
    PLASMIDS
    Addgene
    CONSTRUCTS WITH SEQUENCES FROM axin2
    Tg(hsp70l:axin2-EGFP), tgbac(axin2:venus)
    MARKER RELATIONSHIPS
    axin2Contained in: [BAC] CH211-196B14 (1) (order this)
    axin2Encodes: [EST] eu48 (1), fb37c08 (1), IMAGE:3818167 (1) (order this)
    [cDNA] MGC:111942 (1) (order this), MGC:195290 (1) (order this)
    SEQUENCE INFORMATION
    Type Accession # Length (bp/aa) Analysis
    RNA RefSeq:NM_131561 (1) 3485bp
    Genomic GenBank:BX088708 (1) 193659bp
    Select Tool
    Polypeptide UniProtKB:B3DKI7 (1) 812aa
    Sequence Clusters UniGene:3727 (1)
    Sequence Information (all 29)
    OTHER axin2 GENE PAGES
  • Alliance (1)
  • Gene:58080 (1)
  • VEGA:OTTDARG00000020301 (1)
  • Ensembl(GRCz10):ENSDARG00000100149 (1)
  • ORTHOLOGY for axin2 (Chr: 3)
    CITATIONS (132)