ZFIN ID: ZDB-GENE-000403-2
Gene Name: axin 2 (conductin, axil)
Gene Symbol: axin2
Previous Names: axil, etID37069.3 (1), wu:fb37c08 (1), zgc:111942
Location: Chr: 3   Details
Nomenclature History
GENE EXPRESSION
All Expression Data: 42 figures from 25 publications
Directly Submitted Expression Data: 7 figures (27 images) from Thisse et al., 2004 [IMAGE:3818167]
  6 figures (19 images) from Thisse et al., 2005 [eu48]
Wild-type Stages, Structures: Blastula:Sphere (4.0h-4.33h) to Adult (90d-730d, breeding adult)
  anatomical structure, brain, central nervous system, diencephalon posterior region (all 31) expand
Curated Microarray Expression: GEO (1)
MUTANTS AND TARGETED KNOCKDOWNS No data available
PHENOTYPE No data available
DISEASE ASSOCIATED WITH axin2 HUMAN ORTHOLOG
Disease Ontology Term OMIM Term OMIM Phenotype ID
colorectal cancer Colorectal cancer, somatic 114500
Oligodontia-colorectal cancer syndrome 608615
GENE ONTOLOGY
Ontology GO Term
Biological Process dorsal/ventral pattern formation (more)
Cellular Component cytoplasm (more)
Molecular Function GTPase activator activity (more)
GO Terms (all 25)
PROTEIN FAMILIES, DOMAINS AND SITES
  • InterPro:IPR001158 (1)
  • InterPro:IPR014936 (1)
  • InterPro:IPR016137 (1)
  • InterPro:IPR024066 (1)
  • InterPro:IPR029071 (1)
  • PROSITE:PS50132 (1)
  • PROSITE:PS50841 (1)
  • Pfam:PF00615 (1)
  • Pfam:PF00778 (1)
  • Pfam:PF08833 (1)
  • TRANSCRIPTS
    Type Name Length (bp) Analysis
    mRNA axin2-001 (1) 3515
    ncRNA axin2-002 (1) 1429
    GENE PRODUCT DESCRIPTION
    ANTIBODIES No data available
    PLASMIDS No data available
    CONSTRUCTS WITH SEQUENCES FROM axin2
    Tg(hsp70l:axin2-EGFP)
    SEGMENT (CLONE AND PROBE) RELATIONSHIPS
    axin2 Contained in: [BAC] CH211-196B14 (1) (order this)
    axin2 Encodes: [EST] eu48 (1), fb37c08 (1), IMAGE:3818167 (1) (order this)
    [cDNA] MGC:111942 (1) (order this), MGC:195290 (1) (order this)
    SEQUENCE INFORMATION
    Type Accession # Length (bp/aa) Analysis
    RNA RefSeq:NM_131561 (1) 3485 bp
    Genomic GenBank:BX088708 (1) 193659 bp
    Select Tool
    Polypeptide UniProtKB:B3DKI7 (1) 812 aa
    Sequence Clusters UniGene:3727 (1)
    Sequence Information (all 29)
    OTHER axin2 GENE PAGES
  • Gene:58080 (1)
  • VEGA:OTTDARG00000020301 (1)
  • Ensembl(Zv9):ENSDARG00000014147 (1)
  • ORTHOLOGY
      Evidence
    Species Symbol Chr (Position) Accession # AA CL
    Zebrafish axin2 3  
    Human AXIN2 17 (17q24.1)
  • OMIM:604025
  • Gene:8313
  • Mouse Axin2 11 ( 71.83 cM)
  • MGI:1270862
  • Gene:12006
  • Orthology Details
    CITATIONS (88)