ZFIN ID: ZDB-GENE-000403-2
Gene Name: axin 2 (conductin, axil)
Gene Symbol: axin2
Sequence Ontology ID : SO:0000704

{{control.fieldName}} Edit

ID: {{control.nomenID}}
{{control.fieldName}}:
Reason:
Comments:

Attributions

{{pub.zdbID}}
Previous Names: axil, etID37069.3 (1), wu:fb37c08 (1), zgc:111942

Add new Alias

Alias
Attribution

Attributions for Alias: {{control.newAlias}}

{{pub.zdbID}}

Delete Alias:

(Including Attributions)
Location: Chr: 3 Mapping Details/Browsers
Nomenclature History
GENE EXPRESSION
All Expression Data: 51 figures from 34 publications
Directly Submitted Expression Data: 7 figures (27 images) from Thisse et al., 2004 [IMAGE:3818167]
  6 figures (19 images) from Thisse et al., 2005 [eu48]
Wild-type Stages, Structures: Blastula:Sphere (4.0h-4.33h) to Adult (90d-730d, breeding adult)
  anatomical structure, brain, brain dorsal region, central nervous system (all 37) expand
Curated Microarray Expression: GEO (1)
MUTATIONS AND SEQUENCE TARGETING REAGENTS
Allele Type Localization Consequence Mutagen Suppliers
sa40180 Point Mutation Unknown Premature Stop ENU
sa40181 Point Mutation Unknown Splice Site ENU
PHENOTYPE No data available
DISEASE ASSOCIATED WITH axin2 HUMAN ORTHOLOG
Disease Ontology Term OMIM Term OMIM Phenotype ID
colorectal cancer Colorectal cancer, somatic 114500
Oligodontia-colorectal cancer syndrome 608615
GENE ONTOLOGY
Ontology GO Term
Biological Process dorsal/ventral pattern formation (more)
Cellular Component cytoplasm (more)
Molecular Function GTPase activator activity (more)
GO Terms (all 8)
PROTEIN FAMILIES, DOMAINS AND SITES
  • InterPro:IPR001158
  • InterPro:IPR014936
  • InterPro:IPR016137
  • InterPro:IPR024066
  • InterPro:IPR029071
  • InterPro:IPR032101
  • PROSITE:PS50132
  • PROSITE:PS50841
  • Pfam:PF00615
  • Pfam:PF00778
  • Pfam:PF08833
  • Pfam:PF16646
  • TRANSCRIPTS
    Type Name Length (bp) Analysis
    mRNA axin2-001 (1) 3515
    ncRNA axin2-002 (1) 1429
    GENE PRODUCT DESCRIPTION
    INTERACTIONS AND PATHWAYS
    ANTIBODIESNo data available
    PLASMIDS
    Addgene
    CONSTRUCTS WITH SEQUENCES FROM axin2
    Tg(hsp70l:axin2-EGFP)
    MARKER RELATIONSHIPS
    axin2Contained in: [BAC] CH211-196B14 (1) (order this)
    axin2Encodes: [EST] eu48 (1), fb37c08 (1), IMAGE:3818167 (1) (order this)
    [cDNA] MGC:111942 (1) (order this), MGC:195290 (1) (order this)
    SEQUENCE INFORMATION
    Type Accession # Length (bp/aa) Analysis
    RNA RefSeq:NM_131561 (1) 3485bp
    Genomic GenBank:BX088708 (1) 193659bp
    Select Tool
    Polypeptide UniProtKB:B3DKI7 812aa
    Sequence Clusters UniGene:3727 (1)
    Sequence Information (all 29)
    OTHER axin2 GENE PAGES
  • Gene:58080 (1)
  • VEGA:OTTDARG00000020301 (1)
  • Ensembl(GRCz10):ENSDARG00000100149 (1)
  • ORTHOLOGY for axin2 (Chr: 3)
    CITATIONS (117)