ZFIN ID: ZDB-GENE-000403-2
Gene Name: axin 2 (conductin, axil)
Gene Symbol: axin2
Previous Names: axil, etID37069.3 (1), wu:fb37c08 (1), zgc:111942
Location: Chr: 3   Details
Nomenclature History
GENE EXPRESSION
All Expression Data: 37 figures from 22 publications
Directly Submitted Expression Data: 7 figures (27 images) from Thisse et al., 2004 [IMAGE:3818167]
  6 figures (19 images) from Thisse et al., 2005 [eu48]
Wild-type Stages, Structures: Blastula:Sphere (4.0h-4.33h) to Adult (90d-730d, breeding adult)
  brain, central nervous system, epithalamus, forebrain neural keel (all 26) expand
Curated Microarray Expression: GEO (1)
MUTANTS AND TARGETED KNOCKDOWNS No data available
PHENOTYPE
Phenotype of Human Orthologue OMIM Phenotype ID
Colorectal cancer, somatic 114500
Oligodontia-colorectal cancer syndrome 608615
GENE ONTOLOGY
Ontology GO Term
Biological Process dorsal/ventral pattern formation (more)
Cellular Component cytoplasm (more)
Molecular Function GTPase activator activity (more)
GO Terms (all 23)
PROTEIN FAMILIES, DOMAINS AND SITES
  • InterPro:IPR000342 (1)
  • InterPro:IPR001158 (1)
  • InterPro:IPR014936 (1)
  • InterPro:IPR016137 (1)
  • InterPro:IPR024066 (1)
  • InterPro:IPR029071 (1)
  • PROSITE:PS50132 (1)
  • PROSITE:PS50841 (1)
  • Pfam:PF00615 (1)
  • Pfam:PF00778 (1)
  • Pfam:PF08833 (1)
  • TRANSCRIPTS
    Type Name Length (bp) Analysis
    mRNA axin2-001 (1) 3515
    ncRNA axin2-002 (1) 1429
    GENE PRODUCT DESCRIPTION
    ANTIBODIES No data available
    PLASMIDS No data available
    CONSTRUCTS WITH SEQUENCES FROM axin2
    Tg(hsp70l:axin2-EGFP)
    SEGMENT (CLONE AND PROBE) RELATIONSHIPS
    axin2 Contained in: [BAC] CH211-196B14 (1) (order this)
    axin2 Encodes: [EST] eu48 (1), fb37c08 (1), IMAGE:3818167 (1) (order this)
    [cDNA] MGC:111942 (1) (order this), MGC:195290 (1) (order this)
    SEQUENCE INFORMATION
    Type Accession # Length (bp/aa) Analysis
    RNA RefSeq:NM_131561 (1) 3485 bp
    Genomic GenBank:BX088708 (1) 193659 bp
    Select Tool
    Polypeptide UniProtKB:B3DKI7 (1) 812 aa
    Sequence Clusters UniGene:3727 (1)
    Sequence Information (all 29)
    OTHER axin2 GENE PAGES
  • Gene:58080 (1)
  • VEGA:OTTDARG00000020301 (1)
  • Ensembl(Zv9):ENSDARG00000014147 (1)
  • ORTHOLOGY
      Evidence
    Species Symbol Chr (Position) Accession # AA CL
    Zebrafish axin2 3  
    Human AXIN2 17 (17q24.1)
  • OMIM:604025
  • Gene:8313
  • Mouse Axin2 11 ( 71.83 cM)
  • MGI:1270862
  • Gene:12006
  • Orthology Details
    CITATIONS (83)