ZFIN ID: ZDB-GENE-000403-2
Gene Name: axin 2 (conductin, axil)
Gene Symbol: axin2

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Previous Names: axil, etID37069.3 (1), wu:fb37c08 (1), zgc:111942

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(Including Attributions)
Location: Chr: 3 Mapping Details/Browsers
Nomenclature History
GENE EXPRESSION
All Expression Data: 47 figures from 30 publications
Directly Submitted Expression Data: 7 figures (27 images) from Thisse et al., 2004 [IMAGE:3818167]
  6 figures (19 images) from Thisse et al., 2005 [eu48]
Wild-type Stages, Structures: Blastula:Sphere (4.0h-4.33h) to Adult (90d-730d, breeding adult)
  anatomical structure, brain, central nervous system, diencephalon dorsal region (all 36) expand
Curated Microarray Expression: GEO (1)
MUTATIONS AND SEQUENCE TARGETING REAGENTS
Allele Type Localization Consequence Mutagen Suppliers
sa40180 Point Mutation Unknown Premature Stop ENU
sa40181 Point Mutation Unknown Splice Site ENU
PHENOTYPE No data available
DISEASE ASSOCIATED WITH axin2 HUMAN ORTHOLOG
Disease Ontology Term OMIM Term OMIM Phenotype ID
colon carcinoma Colorectal cancer, somatic 114500
colorectal cancer Colorectal cancer, somatic 114500
Oligodontia-colorectal cancer syndrome 608615
GENE ONTOLOGY
Ontology GO Term
Biological Process dorsal/ventral pattern formation (more)
Cellular Component cytoplasm (more)
Molecular Function GTPase activator activity (more)
GO Terms (all 23)
PROTEIN FAMILIES, DOMAINS AND SITES
  • InterPro:IPR001158 (1)
  • InterPro:IPR014936 (1)
  • InterPro:IPR016137 (1)
  • InterPro:IPR024066 (1)
  • InterPro:IPR029071 (1)
  • InterPro:IPR032101 (1)
  • PROSITE:PS50132 (1)
  • PROSITE:PS50841 (1)
  • Pfam:PF00615 (1)
  • Pfam:PF00778 (1)
  • Pfam:PF08833 (1)
  • Pfam:PF16646 (1)
  • TRANSCRIPTS
    Type Name Length (bp) Analysis
    mRNA axin2-001 (1) 3515
    ncRNA axin2-002 (1) 1429
    GENE PRODUCT DESCRIPTION
    INTERACTIONS AND PATHWAYSNo data available
    ANTIBODIESNo data available
    PLASMIDSNo data available
    CONSTRUCTS WITH SEQUENCES FROM axin2
    Tg(hsp70l:axin2-EGFP)
    SEGMENT (CLONE AND PROBE) RELATIONSHIPS
    axin2Contained in: [BAC] CH211-196B14 (1) (order this)
    axin2Encodes: [EST] eu48 (1), fb37c08 (1), IMAGE:3818167 (1) (order this)
    [cDNA] MGC:111942 (1) (order this), MGC:195290 (1) (order this)
    SEQUENCE INFORMATION
    Type Accession # Length (bp/aa) Analysis
    RNA RefSeq:NM_131561 (1) 3485bp
    Genomic GenBank:BX088708 (1) 193659bp
    Select Tool
    Polypeptide UniProtKB:B3DKI7 (1) 812aa
    Sequence Clusters UniGene:3727 (1)
    Sequence Information (all 28)
    OTHER axin2 GENE PAGES
  • Gene:58080 (1)
  • VEGA:OTTDARG00000020301 (1)
  • Ensembl(GRCz10):ENSDARG00000100149 (1)
  • ORTHOLOGY for axin2 (Chr: 3)
    Species Symbol Chromosome Accession # Evidence
    Human AXIN2 17
  • Gene:8313
  • OMIM:604025
  • HGNC:904
  • Amino acid sequence comparison (1)
    Conserved genome location (synteny) (1)
    Mouse Axin2 11
  • MGI:1270862
  • Gene:12006
  • Amino acid sequence comparison (1)
    Conserved genome location (synteny) (1)
    Download Curated Orthology
    CITATIONS (105)