ZFIN ID: ZDB-GENE-011128-4
Gene Name: jagged canonical Notch ligand 1b
Gene Symbol: jag1b
Sequence Ontology ID : SO:0000704

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Previous Names: jag3, jagged1b, kmi (1), puc, unp1069

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(Including Attributions)
Location: Chr: 13 Mapping Details/Browsers
Nomenclature History
AUTOMATED DESCRIPTION
Predicted to have Notch binding activity and calcium ion binding activity; involved in several processes, including animal organ development, cranial skeletal system development, and dorsal/ventral  ...
GENE EXPRESSION
All Expression Data: 27 figures from 23 publications
Wild-type Stages, Structures: Gastrula:50%-epiboly (5.25h-5.66h) to Adult (90d-730d, breeding adult)
 
Curated Microarray Expression: GEO (1)
MUTATIONS AND SEQUENCE TARGETING REAGENTS
Allele Type Localization Consequence Mutagen Suppliers
b1105 Unknown Unknown Unknown ENU
gd2Gt Transgenic Insertion Unknown Unknown DNA
  • China Zebrafish Resource Center (CZRC, ZKO consortium) (order this)
  • jj59 Point Mutation Donor Splice Site Frameshift ENU
  • Zebrafish International Resource Center (ZIRC) (order this)
  • la018582Tg Transgenic Insertion Unknown Unknown DNA
  • Zebrafish International Resource Center (ZIRC) (order this)
  • la018583Tg Transgenic Insertion Unknown Unknown DNA
    sa17080 Point Mutation Unknown Splice Site ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • Zebrafish International Resource Center (ZIRC) (order this)
  • sa18567 Point Mutation Unknown Splice Site ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • Zebrafish International Resource Center (ZIRC) (order this)
  • sa42247 Point Mutation Unknown Splice Site ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • Zebrafish International Resource Center (ZIRC) (order this)
  • Targeting reagents:
    PHENOTYPE
    Data: 15 figures from 7 publications
    Observed in:
    DISEASE ASSOCIATED WITH jag1b HUMAN ORTHOLOG
    Disease Ontology Term OMIM Term OMIM Phenotype ID
    Alagille syndrome Alagille syndrome 1 118450
    tetralogy of Fallot Tetralogy of Fallot 187500
    ?Deafness, congenital heart defects, and posterior embryotoxon 617992
    ?Deafness, congenital heart defects, and posterior embryotoxon 617992
    DISEASE ASSOCIATED WITH jag1b VIA EXPERIMENTAL MODELS No data available
    GENE ONTOLOGY
    Ontology GO Term
    Biological Process cartilage development involved in endochondral bone morphogenesis (more)
    Cellular Component integral component of membrane (more)
    Molecular Function calcium ion binding (more)
    GO Terms (all 22)
    PROTEIN FAMILIES, DOMAINS AND SITES
  • InterPro:IPR000152 (1)
  • InterPro:IPR000742 (1)
  • InterPro:IPR001007 (1)
  • InterPro:IPR001774 (1)
  • InterPro:IPR001881 (1)
  • InterPro:IPR009030 (1)
  • InterPro:IPR011651 (1)
  • InterPro:IPR013032 (1)
  • InterPro:IPR018097 (1)
  • InterPro:IPR026219 (1)
  • PROSITE:PS00010 (1)
  • PROSITE:PS00022 (1)
  • PROSITE:PS01186 (1)
  • PROSITE:PS01187 (1)
  • PROSITE:PS50026 (1)
  • PROSITE:PS51051 (1)
  • Pfam:PF00008 (1)
  • Pfam:PF01414 (1)
  • Pfam:PF07645 (1)
  • Pfam:PF07657 (1)
  • Pfam:PF12661 (1)
  • TRANSCRIPTS
    Type Name Length (bp) Analysis
    mRNA jag1b-001 (1) 6754
    GENE PRODUCT DESCRIPTION
    INTERACTIONS AND PATHWAYS
    SignaFish
    ANTIBODIES
    PLASMIDSNo data available
    CONSTRUCTS WITH SEQUENCES FROM jag1b No data available
    MARKER RELATIONSHIPS
    jag1bContained in: [BAC] CH211-159E5 (1) (order this)
    SEQUENCE INFORMATION
    Type Accession # Length (bp/aa) Analysis
    RNA RefSeq:NM_131863 (1) 6857bp
    Genomic GenBank:CU138575 (1) 156198bp
    Select Tool
    Polypeptide UniProtKB:A1A3Y7 (1) 1213aa
    Sequence Clusters UniGene:12589 (1)
    Sequence Information (all 13)
    OTHER jag1b GENE PAGES
  • Alliance (1)
  • Gene:140423 (1)
  • VEGA:OTTDARG00000027795 (1)
  • Ensembl(GRCz11):ENSDARG00000013168 (2)
  • ORTHOLOGY for jag1b (Chr: 13)
    CITATIONS (78)