FIGURE
Fig. S3
- ID
- ZDB-FIG-171018-30
- Publication
- Shim et al., 2017 - Development of zebrafish medulloblastoma-like PNET model by TALEN-mediated somatic gene inactivation
- Other Figures
- All Figure Page
- Back to All Figure Page
Fig. S3
TALEN-mediated mutations of rb1 resulted in a marked enlarged liver in zebrafish larvae. Homozygous rb1 mutant larvae were generated by incrossing heterozygous F1 zebrafish with same frameshift mutated alleles (11bp deletion). rb1 mutants exhibited flattened swimming bladder, and enlarged liver at 7 day post fertilization (dpf) and did not survive until 10 dpf (red broken line). The increased lipid accumulation in liver of rb1 mutants was visualized by Oil Red O staining. WT: wild type embryo, rb1–/–: homozygous rb1 mutant. |
Expression Data
Expression Detail
Antibody Labeling
Phenotype Data
| Fish: | |
|---|---|
| Observed In: | |
| Stage: | Days 7-13 |
Phenotype Detail
Acknowledgments
This image is the copyrighted work of the attributed author or publisher, and
ZFIN has permission only to display this image to its users.
Additional permissions should be obtained from the applicable author or publisher of the image.
Full text @ Oncotarget