ZFIN Figure: Du et al., 2017, Fig. 3

ZFIN ID: ZDB-FIG-171003-2

ZFIN ID: ZDB-FIG-171003-2

Du et al., 2017 - C1qr and C1qrl redundantly regulate angiogenesis in zebrafish through controlling endothelial Cdh5. Biochemical and Biophysical Research Communications 483(1):482-487 Full text @ Biochem. Biophys. Res. Commun.

ADDITIONAL FIGURES

EXPRESSION / LABELING:

Genes:	efnb2a ephb4a etsrp vegfaa
Fish:	WT zf745Tg ; cd93^cq29/cq29 ; clec14a^cq30/cq30
Anatomical Terms:	dorsal aorta endothelial cell posterior cardinal vein trunk vasculature
Stage:	Prim-5

PHENOTYPE:

Fish:	cd93^cq29/cq29 ; zf745Tg zf745Tg ; clec14a^cq30/cq30 zf745Tg ; cd93^cq29/cq29 ; clec14a^cq30/cq30
Observed In:	epicardium heart contraction heart development intersegmental vein whole organism
Stage Range:	Prim-25 to Days 7-13

Fig. 3 ZFIN is incorporating published figure images and captions as part of an ongoing project. Figures from some publications have not yet been curated, or are not available for display because of copyright restrictions.

Gene Expression Details

Gene	Fish	Conditions	Stage	Anatomy	Assay
efnb2a	WT	standard conditions	Prim-5	dorsal aorta	ISH
			Prim-5	endothelial cell	ISH
	zf745Tg ; cd93^cq29/cq29 ; clec14a^cq30/cq30	standard conditions	Prim-5	dorsal aorta	ISH
			Prim-5	endothelial cell	ISH
ephb4a	WT	standard conditions	Prim-5	posterior cardinal vein	ISH
	zf745Tg ; cd93^cq29/cq29 ; clec14a^cq30/cq30	standard conditions	Prim-5	posterior cardinal vein	ISH
etsrp	WT	standard conditions	Prim-5	endothelial cell	ISH
	zf745Tg ; cd93^cq29/cq29 ; clec14a^cq30/cq30	standard conditions	Prim-5	endothelial cell	ISH
vegfaa	WT	standard conditions	Prim-5	trunk vasculature	ISH
	zf745Tg ; cd93^cq29/cq29 ; clec14a^cq30/cq30	standard conditions	Prim-5	trunk vasculature	ISH

Antibody Labeling Details No data available

Phenotype Details

Fish	Conditions	Stage	Phenotype
cd93^cq29/cq29 ; zf745Tg	standard conditions	Prim-25	intersegmental vein morphology, abnormal
		Protruding-mouth	heart development process quality, normal
		Protruding-mouth	intersegmental vein morphology, abnormal
		Day 4	epicardium increased size, abnormal
		Day 4	heart contraction decreased rate, abnormal
zf745Tg ; cd93^cq29/cq29 ; clec14a^cq30/cq30	standard conditions	Prim-25	intersegmental vein morphology, abnormal
		Pec-fin	epicardium increased size, abnormal
		Pec-fin	heart contraction decreased rate, abnormal
		Day 5 - Days 7-13	whole organism decreased life span, abnormal
zf745Tg ; clec14a^cq30/cq30	standard conditions	Prim-25	intersegmental vein morphology, abnormal
		Protruding-mouth	heart development process quality, normal
		Protruding-mouth	intersegmental vein morphology, abnormal
		Day 4	epicardium increased size, abnormal
		Day 4	heart contraction decreased rate, abnormal

Full text @ Biochem. Biophys. Res. Commun.