ZFIN ID: ZDB-GENE-990415-62
Gene Name: eph receptor B4a
Gene Symbol: ephb4a
Sequence Ontology ID : SO:0000704

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Previous Names: ephB4 (1), ephB4a, cb646 (1), rtk5

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(Including Attributions)
Location: Chr: 5 Mapping Details/Browsers
AUTOMATED DESCRIPTION
Predicted to have transmembrane-ephrin receptor activity; involved in angioblast cell migration involved in selective angioblast sprouting, convergent extension, and ephrin receptor signaling  ...
GENE EXPRESSION
All Expression Data: 33 figures from 27 publications
Directly Submitted Expression Data: 6 figures (39 images) from Thisse et al., 2001 [cb646]
Wild-type Stages, Structures: Gastrula:50%-epiboly (5.25h-5.66h) to Hatching:Long-pec (48.0h-60.0h)
 
Curated Microarray Expression: GEO (1)
PHENOTYPE
Data: 8 figures from 5 publications
Observed in:
DISEASE ASSOCIATED WITH ephb4a HUMAN ORTHOLOG
Disease Ontology Term OMIM Term OMIM Phenotype ID
Lymphatic malformation 7 617300
Lymphatic malformation 7 617300
Capillary malformation-arteriovenous malformation 2 618196
Capillary malformation-arteriovenous malformation 2 618196
DISEASE ASSOCIATED WITH ephb4a VIA EXPERIMENTAL MODELS
Human Disease Fish Conditions Citations
lymphatic system disease y1Tg + MO4-ephb4a standard conditions Li et al., 2018
y1Tg + MO2-ephb4a standard conditions Li et al., 2018
GENE ONTOLOGY
Ontology GO Term
Biological Process blood vessel development (more)
Cellular Component integral component of membrane (more)
Molecular Function ATP binding (more)
GO Terms (all 20)
PROTEIN FAMILIES, DOMAINS AND SITES
  • InterPro:IPR000719 (1)
  • InterPro:IPR001090 (1)
  • InterPro:IPR001245 (1)
  • InterPro:IPR001426 (1)
  • InterPro:IPR001660 (1)
  • InterPro:IPR003961 (1)
  • InterPro:IPR008266 (1)
  • InterPro:IPR008979 (1)
  • InterPro:IPR009030 (1)
  • InterPro:IPR011009 (1)
  • InterPro:IPR011641 (1)
  • InterPro:IPR013761 (1)
  • InterPro:IPR013783 (1)
  • InterPro:IPR016257 (1)
  • InterPro:IPR017441 (1)
  • InterPro:IPR020635 (1)
  • InterPro:IPR027936 (1)
  • InterPro:IPR034290 (1)
  • InterPro:IPR036116 (1)
  • InterPro:IPR037636 (1)
  • PROSITE:PS00107 (1)
  • PROSITE:PS00109 (1)
  • PROSITE:PS00791 (1)
  • PROSITE:PS50011 (1)
  • PROSITE:PS50105 (1)
  • PROSITE:PS50853 (1)
  • PROSITE:PS51550 (1)
  • Pfam:PF00041 (1)
  • Pfam:PF00536 (1)
  • Pfam:PF01404 (1)
  • Pfam:PF07714 (1)
  • Pfam:PF14575 (1)
  • EC:2.7.10.1 (1)
  • TRANSCRIPTS
    Type Name Length (bp) Analysis
    mRNA ephb4a-201 (1) 2940
    ephb4a-202 (1) 1308
    GENE PRODUCT DESCRIPTION
    INTERACTIONS AND PATHWAYS
    ANTIBODIESNo data available
    PLASMIDSNo data available
    CONSTRUCTS WITH SEQUENCES FROM ephb4a
    MARKER RELATIONSHIPS
    ephb4aContained in: [Fosmid] CH1073-264G23 (1) (order this), ZFOS-1566H6 (1)
    ephb4aContains: [STS] unp162
    ephb4aEncodes: [EST] cb646 (1) (order this)
    [cDNA] MGC:136748 (1) (order this), MGC:171234 (1) (order this)
    SEQUENCE INFORMATION
    Type Accession # Length (bp/aa) Analysis
    RNA RefSeq:NM_131414 (1) 3055bp
    Genomic GenBank:FO904976 (1) 34139bp
    Select Tool
    Polypeptide UniProtKB:A0A2R8QG60 (1) 987aa
    Sequence Clusters UniGene:5764 (1)
    Sequence Information (all 37)
    OTHER ephb4a GENE PAGES
  • Alliance (1)
  • Gene:30688 (1)
  • VEGA:OTTDARG00000029266 (1)
  • Ensembl(GRCz11):ENSDARG00000100725 (1)
  • ORTHOLOGY for ephb4a (Chr: 5)
    CITATIONS (86)