ZFIN ID: ZDB-GENE-990415-273
Gene Name: vascular endothelial growth factor Aa
Gene Symbol: vegfaa
Sequence Ontology ID : SO:0000704

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Previous Names: vegf-a (1), vegf (1), vegfa (1), etID309976.16 (1), wu:fj82c06

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(Including Attributions)
Location: Chr: 16 Mapping Details/Browsers
Nomenclature History
AUTOMATED DESCRIPTION
Exhibits growth factor activity; involved in several processes, including animal organ development, circulatory system development, and regulation of vasculature development; predicted to localize to  ...
GENE EXPRESSION
All Expression Data: 82 figures from 67 publications
Wild-type Stages, Structures: Zygote:1-cell (0.0h-0.75h) to Adult (90d-730d, breeding adult)
 
Curated Microarray Expression: GEO (1)
MUTATIONS AND SEQUENCE TARGETING REAGENTS
Allele Type Localization Consequence Mutagen Suppliers
bns1 Small Deletion Unknown Frameshift, Premature Stop TALEN
zf1090 Small Deletion Unknown Unknown TALEN
zf1091 Small Deletion Unknown Unknown TALEN
Targeting reagents:
PHENOTYPE
Data: 34 figures from 21 publications
Observed in:
DISEASE ASSOCIATED WITH vegfaa HUMAN ORTHOLOG
Disease Ontology Term OMIM Term OMIM Phenotype ID
{Microvascular complications of diabetes 1} 603933
DISEASE ASSOCIATED WITH vegfaa VIA EXPERIMENTAL MODELS No data available
GENE ONTOLOGY
Ontology GO Term
Biological Process activation of phospholipase C activity (more)
Cellular Component extracellular region (more)
Molecular Function protein binding (more)
GO Terms (all 44)
PROTEIN FAMILIES, DOMAINS AND SITES
  • InterPro:IPR000072 (1)
  • InterPro:IPR023581 (1)
  • InterPro:IPR027928 (1)
  • InterPro:IPR029034 (1)
  • InterPro:IPR036841 (1)
  • PROSITE:PS00249 (1)
  • PROSITE:PS50278 (1)
  • Pfam:PF00341 (1)
  • Pfam:PF14554 (1)
  • TRANSCRIPTS
    Type Name Length (bp) Analysis
    mRNA vegfaa-201 (1) 2658
    GENE PRODUCT DESCRIPTION
    INTERACTIONS AND PATHWAYS
    SignaFish
    ANTIBODIES
    PLASMIDS
    Addgene
    CONSTRUCTS WITH SEQUENCES FROM vegfaa
    MARKER RELATIONSHIPS
    vegfaaContained in: [BAC] CH211-169N14 (order this)
    vegfaaEncodes: [EST] fj82c06
    [cDNA] MGC:193838 (1) (order this), MGC:193849 (1) (order this)
    SEQUENCE INFORMATION
    Type Accession # Length (bp/aa) Analysis
    RNA RefSeq:NM_131408 (1) 567bp
    Genomic GenBank:BX470147 (1) 151584bp
    Select Tool
    Polypeptide UniProtKB:O73682 (1) 188aa
    Sequence Clusters UniGene:150231 (1)
    Sequence Information (all 30)
    OTHER vegfaa GENE PAGES
  • Alliance (1)
  • Gene:30682 (1)
  • VEGA:OTTDARG00000031190 (1)
  • Ensembl(GRCz11):ENSDARG00000103542 (1)
  • ORTHOLOGY for vegfaa (Chr: 16)
    CITATIONS (264)