ZFIN ID: ZDB-FIG-160630-29
Lovely et al., 2016 - Bmp signaling mediates endoderm pouch morphogenesis by regulating Fgf signaling in zebrafish. Development (Cambridge, England)   143(11):2000-11 Full text @ Development
ADDITIONAL FIGURES
PHENOTYPE:
Fish:
Condition:
Observed In:
Stage Range: 14-19 somites to Prim-5

Fig. 6

Bmp signaling regulates pouch morphogenesis. Still images from confocal time-lapse movies of sox17:dsred; sox10:EGFP double-transgenic embryos. (A,A′,F,F′) 18hpf embryos at the initiation of the movie (T0). (A-E′) Pouches (arrows) form in a sequential fashion to segregate the pharyngeal arches (arrowheads) in control embryos. (F-J′) In Dorsomorphin-treated embryos, pouch formation and arch segmentation fail. Lateral views, anterior to the left. Scale bar: 50┬Ám.

Gene Expression Details No data available
Antibody Labeling Details No data available
Phenotype Details
Fish Conditions Stage Phenotype
s903Tg ; ba2Tg chemical treatment: dorsomorphin 14-19 somites pharyngeal arch 1 morphology, abnormal
14-19 somites pharyngeal arch 2 morphology, abnormal
14-19 somites pharyngeal pouch 1 hypoplastic, abnormal
14-19 somites pharyngeal system development disrupted, abnormal
20-25 somites pharyngeal pouch 1 hypoplastic, abnormal
20-25 somites pharyngeal pouch 2 hypoplastic, abnormal
20-25 somites pharyngeal system development disrupted, abnormal
Prim-5 pharyngeal arch 3-7 hypoplastic, abnormal
Prim-5 pharyngeal pouch 1 hypoplastic, abnormal
Prim-5 pharyngeal pouches 2-6 hypoplastic, abnormal
Prim-5 pharyngeal system development disrupted, abnormal
Acknowledgments:
ZFIN wishes to thank the journal Development (Cambridge, England) for permission to reproduce figures from this article. Please note that this material may be protected by copyright. Full text @ Development