ZFIN ID: ZDB-FIG-160630-29
Lovely et al., 2016 - Bmp signaling mediates endoderm pouch morphogenesis by regulating Fgf signaling in zebrafish. Development (Cambridge, England)   143(11):2000-11 Full text @ Development
ADDITIONAL FIGURES
PHENOTYPE:
Fish:
Condition:
Observed In:
Stage Range: 14-19 somites to Prim-5

Fig. 6

Bmp signaling regulates pouch morphogenesis. Still images from confocal time-lapse movies of sox17:dsred; sox10:EGFP double-transgenic embryos. (A,A′,F,F′) 18hpf embryos at the initiation of the movie (T0). (A-E′) Pouches (arrows) form in a sequential fashion to segregate the pharyngeal arches (arrowheads) in control embryos. (F-J′) In Dorsomorphin-treated embryos, pouch formation and arch segmentation fail. Lateral views, anterior to the left. Scale bar: 50┬Ám.

Gene Expression Details No data available
Antibody Labeling Details No data available
Phenotype Details
Fish Conditions Stage Phenotype
ba2Tg; s903Tg chemical treatment: dorsomorphin 14-19 somites pharyngeal arch 1 morphology, abnormal
14-19 somites pharyngeal arch 2 morphology, abnormal
14-19 somites pharyngeal pouch 1 hypoplastic, abnormal
14-19 somites pharyngeal system development disrupted, abnormal
20-25 somites pharyngeal pouch 1 hypoplastic, abnormal
20-25 somites pharyngeal pouch 2 hypoplastic, abnormal
20-25 somites pharyngeal system development disrupted, abnormal
Prim-5 pharyngeal arch 3-7 hypoplastic, abnormal
Prim-5 pharyngeal pouch 1 hypoplastic, abnormal
Prim-5 pharyngeal pouches 2-6 hypoplastic, abnormal
Prim-5 pharyngeal system development disrupted, abnormal
Acknowledgments:
This image is the copyrighted work of the attributed author or publisher, and ZFIN has permission only to display this image to its users. Additional permissions should be obtained from the applicable author or publisher of the image. Full text @ Development