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ZFIN ID: ZDB-FIG-160630-31
Lovely et al., 2016 - Bmp signaling mediates endoderm pouch morphogenesis by regulating Fgf signaling in zebrafish. Development (Cambridge, England)   143(11):2000-11 Full text @ Development
ADDITIONAL FIGURES
PHENOTYPE:
Fish:
Condition:
Observed In:
Stage Range: 14-19 somites to Prim-25

Fig. 8

Blocking Bmp reduces the Fgf signaling response in the forming pouch. Still images from confocal time-lapse movies of sox17:dsred; dusp6:d2GFP (Fgf-responsive cells) double-transgenic embryos. (A-A′′,F-F′′) Embryos at 18hpf, the initiation of the movie (T0). Arrows indicate overlap between transgene expression, whereas arrowheads indicate lack of overlap. (F-J′′) Dorsomorphin-treated embryos show a reduced Fgf signaling response in the endoderm and pouches fail to form, in contrast to controls (A-E′′). Lateral views, anterior to the left. Scale bar: 50┬Ám.

Gene Expression Details No data available
Antibody Labeling Details No data available
Phenotype Details
Fish Conditions Stage Phenotype
pt6Tg ; s903Tg chemical treatment: dorsomorphin 14-19 somites pharyngeal system development disrupted, abnormal
20-25 somites pharyngeal system development disrupted, abnormal
Prim-5 pharyngeal system development disrupted, abnormal
Prim-15 pharyngeal system development disrupted, abnormal
Prim-25 pharyngeal pouch hypoplastic, abnormal
Prim-25 pharyngeal system development disrupted, abnormal
Acknowledgments:
ZFIN wishes to thank the journal Development (Cambridge, England) for permission to reproduce figures from this article. Please note that this material may be protected by copyright. Full text @ Development