ZFIN ID: ZDB-FIG-160630-31
Lovely et al., 2016 - Bmp signaling mediates endoderm pouch morphogenesis by regulating Fgf signaling in zebrafish. Development (Cambridge, England)   143(11):2000-11 Full text @ Development
ADDITIONAL FIGURES
PHENOTYPE:
Fish:
Condition:
Observed In:
Stage Range: 14-19 somites to Prim-25

Fig. 8

Blocking Bmp reduces the Fgf signaling response in the forming pouch. Still images from confocal time-lapse movies of sox17:dsred; dusp6:d2GFP (Fgf-responsive cells) double-transgenic embryos. (A-A′′,F-F′′) Embryos at 18hpf, the initiation of the movie (T0). Arrows indicate overlap between transgene expression, whereas arrowheads indicate lack of overlap. (F-J′′) Dorsomorphin-treated embryos show a reduced Fgf signaling response in the endoderm and pouches fail to form, in contrast to controls (A-E′′). Lateral views, anterior to the left. Scale bar: 50┬Ám.

Gene Expression Details No data available
Antibody Labeling Details No data available
Phenotype Details
Fish Conditions Stage Phenotype
pt6Tg; s903Tg chemical treatment: dorsomorphin 14-19 somites pharyngeal system development disrupted, abnormal
20-25 somites pharyngeal system development disrupted, abnormal
Prim-5 pharyngeal system development disrupted, abnormal
Prim-15 pharyngeal system development disrupted, abnormal
Prim-25 pharyngeal pouch hypoplastic, abnormal
Prim-25 pharyngeal system development disrupted, abnormal
Acknowledgments:
This image is the copyrighted work of the attributed author or publisher, and ZFIN has permission only to display this image to its users. Additional permissions should be obtained from the applicable author or publisher of the image. Full text @ Development