ZFIN ID: ZDB-FIG-151130-36
Swindell et al., 2015 - Crispld2 is required for neural crest cell migration and cell viability during zebrafish craniofacial development. Genesis (New York, N.Y. : 2000)   53(10):660-7 Full text @ Genesis
ADDITIONAL FIGURES
PHENOTYPE:
Fish:
Knockdown Reagents:
Observed In:
Stage Range: 14-19 somites to Protruding-mouth

Fig. 3

Increased apoptosis is present in the head of MO3 injected embryos. Co-injection of MO3 with p53MO and whole mount TUNEL staining shows partial inhibition of MO3-induced apoptosis. Lateral view of UIC (a–f), MO3-injected embryos (g–l), MO3/p53MO co-injected embryos (m–r), and control MM-MO3-injected embryos (s–x), at 16 hpf (a, g, m, s), 24 hpf (b, h, n, t), 36 hpf (c, i, o, u), 48 hpf (d, j, p, v), 60 hpf (e, k, q, w), and 72 hpf (f, l, r, x).

Gene Expression Details No data available
Antibody Labeling Details No data available
Phenotype Details
Fish Conditions Stage Phenotype
WT + MO3-crispld2 standard conditions 14-19 somites head apoptotic process increased occurrence, abnormal
Prim-5 head apoptotic process increased occurrence, abnormal
Prim-25 head apoptotic process increased occurrence, abnormal
Long-pec head apoptotic process increased occurrence, abnormal
Pec-fin head apoptotic process increased occurrence, abnormal
Protruding-mouth head apoptotic process increased occurrence, abnormal
WT + MO3-crispld2 + MO4-tp53 standard conditions 14-19 somites head apoptotic process increased occurrence, abnormal
Prim-5 head apoptotic process increased occurrence, abnormal
Prim-25 head apoptotic process increased occurrence, abnormal
Long-pec head apoptotic process increased occurrence, abnormal
Pec-fin head apoptotic process increased occurrence, abnormal
Protruding-mouth head apoptotic process increased occurrence, abnormal
Acknowledgments:
ZFIN wishes to thank the journal Genesis (New York, N.Y. : 2000) for permission to reproduce figures from this article. Please note that this material may be protected by copyright. Full text @ Genesis