| ZFIN ID: ZDB-FIG-151130-34 |
Swindell et al., 2015
- Crispld2 is required for neural crest cell migration and cell viability during zebrafish craniofacial development.
Genesis (New York, N.Y. : 2000)
53(10):660-7
Full text @ Genesis
EXPRESSION / LABELING:
| Gene: | |
|---|---|
| Fish: | |
| Knockdown Reagent: | |
| Anatomical Term: | |
| Stage Range: | 14-19 somites to Prim-5 |
PHENOTYPE:
| Fish: | |
|---|---|
| Knockdown Reagent: | |
| Observed In: | |
| Stage Range: | 14-19 somites to Prim-5 |
Fig. 1 NCC migration is disorganized in MO3 morphants. Time-lapse live cell imaging captures of sox10:GFP embryos showing migrating NCC cells at 16 (a, b), 22 (c, d), and 28 hpf (e, f). UIC (a, c, and e) and MO3-injected embryos (b, d, and f) showing a dorsal view of migrating NCCs. White arrows point to abnormally migrating NCCs. (g) Quantification of number of cells crossing the midline in UIC, MO3 and control MM-MO3 injected embryos. |
Gene Expression Details
| Gene | Antibody | Fish | Conditions | Stage | Anatomy | Assay |
|---|---|---|---|---|---|---|
| EGFP | ba2Tg | standard conditions | 14-19 somites | neural crest cell | IFL | |
| 26+ somites | neural crest cell | IFL | ||||
| Prim-5 | neural crest cell | IFL | ||||
| ba2Tg + MO3-crispld2 | standard conditions | 14-19 somites | neural crest cell | IFL | ||
| 26+ somites | neural crest cell | IFL | ||||
| Prim-5 | neural crest cell | IFL |
Antibody Labeling Details
No data available
Phenotype Details
| Acknowledgments: | This image is the copyrighted work of the attributed author or publisher, and ZFIN has permission only to display this image to its users. Additional permissions should be obtained from the applicable author or publisher of the image. Full text @ Genesis |
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