ZFIN ID: ZDB-FIG-151130-35
Swindell et al., 2015 - Crispld2 is required for neural crest cell migration and cell viability during zebrafish craniofacial development. Genesis (New York, N.Y. : 2000)   53(10):660-7 Full text @ Genesis
ADDITIONAL FIGURES
EXPRESSION / LABELING:
Gene:
Fish:
Knockdown Reagent:
Anatomical Term:
Stage Range: Long-pec to Protruding-mouth
PHENOTYPE:
Fish:
Knockdown Reagent:
Observed In:
Stage Range: Pec-fin to Protruding-mouth

Fig. 2

Aberrant oral cartilage in MO3 morphants. Time-lapse live cell imaging captures of sox10:GFP embryos showing migrating NCC cells at 48 (a, b), 60 (c, d), and 72 hpf (e, f). UIC (a, c, and e) and MO3-injected embryos (b, d, and f) showing a ventral view of migrating NCCs. White arrows point to loss of normal migration and abnormal formation of presumptive cartilage elements.

Gene Expression Details
Gene Antibody Fish Conditions Stage Anatomy Assay
EGFP ba2Tg standard conditions Long-pec pharyngeal arch cartilage IFL
Pec-fin pharyngeal arch cartilage IFL
Protruding-mouth pharyngeal arch cartilage IFL
ba2Tg + MO3-crispld2 standard conditions Long-pec pharyngeal arch cartilage IFL
Pec-fin pharyngeal arch cartilage IFL
Protruding-mouth pharyngeal arch cartilage IFL
Antibody Labeling Details No data available
Phenotype Details
Fish Conditions Stage Phenotype
ba2Tg + MO3-crispld2 standard conditions Pec-fin embryonic viscerocranium morphogenesis decreased process quality, abnormal
Pec-fin pharyngeal arch cartilage malformed, abnormal
Protruding-mouth embryonic viscerocranium morphogenesis decreased process quality, abnormal
Protruding-mouth pharyngeal arch cartilage malformed, abnormal
Acknowledgments:
ZFIN wishes to thank the journal Genesis (New York, N.Y. : 2000) for permission to reproduce figures from this article. Please note that this material may be protected by copyright. Full text @ Genesis