ZFIN ID: ZDB-FIG-151130-37
Swindell et al., 2015 - Crispld2 is required for neural crest cell migration and cell viability during zebrafish craniofacial development. Genesis (New York, N.Y. : 2000)   53(10):660-7 Full text @ Genesis
Knockdown Reagent:
Observed In:
Stage Range: 14-19 somites to Long-pec

Fig. 4

Cell proliferation is unchanged in MO3 injected embryos. Whole mount immunohistochemistry with mitotic marker anti-phosphohistone H3 shows proliferating cells in developing embryos. UIC (a–c), MO3 (d–f), and control MM-MO3-injected embryos (g–i) embryos at 16 hpf (a, d, g), 24 hpf (b, e, h), and 48 hpf (c, f, i). (j) Quantification of number of proliferating cells in UIC, MO3, and control MM-MO3 injected embryos at 16 and 24 hpf.

Gene Expression Details No data available
Antibody Labeling Details No data available
Phenotype Details
Fish Conditions Stage Phenotype
WT + MO3-crispld2 standard conditions 14-19 somites head cell population proliferation occurrence, normal
Prim-5 head cell population proliferation occurrence, normal
Prim-5 pharyngeal arch 3-7 cell population proliferation decreased occurrence, abnormal
Long-pec head cell population proliferation occurrence, normal
ZFIN wishes to thank the journal Genesis (New York, N.Y. : 2000) for permission to reproduce figures from this article. Please note that this material may be protected by copyright. Full text @ Genesis