ZFIN Fish: ba2Tg

ZFIN ID: ZDB-FISH-150901-15643

Fish name:	ba2Tg
Genotype:	ba2Tg
Targeting Reagent:	none

HUMAN DISEASE MODELED by ba2Tg
No data available

GENE EXPRESSION
Gene expression in ba2Tg

RNA expression

Expressed Gene	Structure	Conditions	Figures
aldoaa	neural crest cell	control	Fig. 2 from Espina et al., 2018
alx1	midbrain cranial neural crest	standard conditions	Fig. 2 from Dee et al., 2013
bhlhe40	oligodendrocyte	standard conditions	Fig. 4 from Chung et al., 2011
cadm3	spinal cord motor neuron	standard conditions	Fig. 8 from Hunter et al., 2011
ccdc3b	oligodendrocyte	standard conditions	Fig. 4 from Chung et al., 2011
ctrb.3	oligodendrocyte	standard conditions	Fig. 4 from Chung et al., 2011
dlg1a	oligodendrocyte	standard conditions	Fig. 4 from Chung et al., 2011
egln3	neural crest cell	control	Fig. 2 from Espina et al., 2018
hif1ab	neural crest cell	control	Fig. 2 from Espina et al., 2018
ldha	neural crest cell	control	Fig. 2 from Espina et al., 2018
pax7a	neural crest cell	standard conditions	Fig. 4 from Minchin et al., 2008
pdgfra	neural crest cell	control	Fig. 2 from Espina et al., 2018
rbp2a	oligodendrocyte	standard conditions	Fig. 4 from Chung et al., 2011
ret	(not) pharyngeal arch cranial neural crest	standard conditions	Fig. 6 from Knight et al., 2011
rock2b	oligodendrocyte	standard conditions	Fig. 4 from Chung et al., 2011
selenop	oligodendrocyte	standard conditions	Fig. 4 from Chung et al., 2011
slc2a1a	neural crest cell	control	Fig. 2 from Espina et al., 2018
snai1b	neural crest cell	control	Fig. 2 from Espina et al., 2018
sox10	neural crest neural crest cell olfactory epithelium microvillous olfactory receptor neuron oligodendrocyte posterior lateral line immature Schwann cell primitive olfactory epithelium microvillous olfactory receptor neuron spinal cord glioblast (sensu Vertebrata)	standard conditions	Fig. 4 from Jurynec et al., 2019 Fig. 3 from Asad et al., 2016 Fig. 4 from Saxena et al., 2013 Fig. 2 from Shin et al., 2012 Fig. 2 from Chung et al., 2011

Protein expression

Antibody	Antigen Genes	Structure	Conditions	Figures
Ab2-smad3		pharyngeal arch anatomical region	standard conditions	Fig. S4 from Abrial et al., 2017
Ab1-lama1		optic furrow basement membrane	standard conditions	Fig. 4 from James et al., 2016
Ab4-GFP		optic furrow	standard conditions	Fig. 4 from James et al., 2016
Ab1-tubg1		chondrocyte centrosome	standard conditions	Fig. 4 from Santos-Ledo et al., 2017
Ab8-rps6		chondrocyte	standard conditions	Fig. 5 from Santos-Ledo et al., 2017
Ab36-h3		pharyngeal arch 1 cell pharyngeal arch 2 cell	control	Fig. 4 from Li et al., 2018
Ab1-cadm3	cadm3	spinal cord motor neuron	standard conditions	Fig. 8 from Hunter et al., 2011
Ab3-sox10	sox10	neural crest cell spinal cord	control	Fig. 3 from Asad et al., 2016
Ab1-sox10		neural crest olfactory epithelium microvillous olfactory receptor neuron posterior lateral line immature Schwann cell primitive olfactory epithelium microvillous olfactory receptor neuron spinal cord glioblast (sensu Vertebrata)	standard conditions	Fig. 4 from Jurynec et al., 2019 Fig. 4 from Saxena et al., 2013 Fig. 2 from Shin et al., 2012

Reporter gene expression

Expressed Gene	Structure	Conditions	Figures
EGFP	ceratohyal cartilage chondrocyte cranial cartilage cranial neural crest cranial neural crest cell enteric nervous system neural crest cell eye anatomical region glioblast (sensu Vertebrata) head medial region intestinal bulb primordium anatomical region mandibular arch skeleton Meckel's cartilage midbrain cranial neural crest migratory neural crest cell myelinating Schwann cell neural crest neural crest cell neurocranial trabecula olfactory epithelium microvillous olfactory receptor neuron oligodendrocyte otic vesicle anatomical region palatoquadrate cartilage pharyngeal arch pharyngeal arch 1 neural crest cell pharyngeal arch 2 neural crest cell pharyngeal arch 2 skeleton pharyngeal arch 3 neural crest pharyngeal arch 3-7 pharyngeal arch 4 neural crest pharyngeal arch 5 neural crest pharyngeal arch cartilage post-vent region neural crest posterior lateral line immature Schwann cell primitive olfactory epithelium microvillous olfactory receptor neuron vagal ganglion anatomical region	standard conditions	47 figures from 31 publications
	cranial neural crest cell (not) neural crest pharyngeal arch 1 neural crest cell pharyngeal arch 2 neural crest cell pharyngeal arch 3 neural crest pharyngeal arch 4 neural crest pharyngeal arch 5 neural crest	chemical treatment: Cyclopamine	Fig. S3 from Abrial et al., 2017 Fig. 7 from Banerjee et al., 2016 Fig. S10 from Tobin et al., 2008
GFP	pharyngeal arch 3 neural crest pharyngeal arch 4 neural crest pharyngeal arch 5 neural crest	standard conditions	Fig. S4 from Abrial et al., 2017

PHENOTYPE
Phenotype in ba2Tg

Phenotype	Conditions	Figures
cranial skeletal system development disrupted, abnormal	chemical treatment: C646	Fig. S1 from Babu et al., 2018
neural crest EGFP expression absent, abnormal	chemical treatment: metformin	Fig. 7 from Banerjee et al., 2016
pharyngeal arch 1 decreased size, abnormal	chemical treatment: C646	Fig. S1 from Babu et al., 2018
pharyngeal arch 2 decreased size, abnormal	chemical treatment: C646	Fig. S1 from Babu et al., 2018
pharyngeal arch 3-7 aplastic/hypoplastic, abnormal	chemical treatment: C646	Fig. S1 from Babu et al., 2018

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