ZFIN ID: ZDB-FIG-150311-50
Blasky et al., 2014 - Pard3 regulates contact between neural crest cells and the timing of Schwann cell differentiation but is not essential for neural crest migration or myelination. Developmental dynamics : an official publication of the American Association of Anatomists   243(12):1511-23 Full text @ Dev. Dyn.
ADDITIONAL FIGURES
PHENOTYPE:
Fish:
Observed In:
Stage Range: 14-19 somites to Prim-5

Fig. 2 Schwann cells exit the dorsal neural tube on schedule in pard3 mutants. Panels show representative frames from time-lapse movies of trunk neural crest cells between 18–24 hpf. Views are from dorsal with anterior to the left. Insets display z-plane orthogonal views of the migrating neural crest for each frame. Numbers denote time elapsed, in minutes, from start of imaging. Embryos are siblings and imaged sequentially in the same chamber. A: Initiation of neural crest migration in a control pard3fh305/+ embryo. Neural crest cells are marked by sox10:memRFP expression. Arrows mark migration on the medial pathway between neural tube and somites and asterisks mark migration on the lateral pathway, across the dorsolateral surface of somites. B: Migration of neural crest in a MZpard3fh305 mutant embryo. The onset and pattern of migration is similar to the control. Scale bar = 50 µM.

Gene Expression Details No data available
Antibody Labeling Details No data available
Phenotype Details
Fish Conditions Stage Phenotype
pard3abfh305/fh305 standard conditions 14-19 somites - Prim-5 neural tube neural crest cell delamination temporal distribution quality, normal
14-19 somites - Prim-5 neural tube neural crest cell migration temporal distribution quality, normal
Acknowledgments:
ZFIN wishes to thank the journal Developmental dynamics : an official publication of the American Association of Anatomists for permission to reproduce figures from this article. Please note that this material may be protected by copyright. Full text @ Dev. Dyn.