ZFIN ID: ZDB-FIG-150224-18
papp-a2-knockdown reduces Notch signaling activity in the CNS. (A) Representative images of control and papp-a2-knockdown Notch activity reporter embryos [Tg(Tp1bglob:eGFP)um13] showing the range of Notch reporter fluorescence levels. Embryos were grouped according to fluorescence levels ranging from 1 (very low Notch signaling activity) to 4 (maximum Notch signaling activity). (B) Plot showing the percentage of embryos at each fluorescence level in control and knockdown embryos. n = 20 (cMO), 24 (e1i1), 30 (ATG), 14 (i3e4). (C) her6 whole-mount in situ hybridization of 24 hpf embryos. Numbers indicate fractions of embryos displaying the depicted phenotype. hb, hindbrain; mb, midbrain.
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