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ZFIN ID: ZDB-FIG-131024-14
Kamel et al., 2013 - Requirement for frzb and fzd7a in cranial neural crest convergence and extension mechanisms during zebrafish palate and jaw morphogenesis. Developmental Biology   381(2):423-33 Full text @ Dev. Biol.
ADDITIONAL FIGURES
EXPRESSION / LABELING:
Genes:
Fish:
Anatomical Terms:
Stage: Long-pec
PHENOTYPE:
Fish:
Observed In:
Stage: Long-pec

Fig. 7 edn1 is required for expression of wnt9a, frzb and fzd7a. Lateral views at 55 hpf (A–F). Wholemount RNA in situ hybridization for wnt9a (A, B), frzb (C, D), fzd7a (E, F) and bapx1 (G, H) in wildtype and edn1-/- mutants. Expression of wnt9a, frzb and bapx1 was absent in the developing pharyngeal arches (B, D, H), while fzd7a expression was strongly reduced in both the forebrain and arches (F) in edn1-/- mutants.

Gene Expression Details
Gene Antibody Fish Conditions Stage Qualifier Anatomy Assay
frzb WT standard conditions Long-pec pharyngeal arch ISH
edn1tf216b/tf216b standard conditions Long-pec Not Detected pharyngeal arch ISH
fzd7a WT standard conditions Long-pec hindbrain ISH
Long-pec pharyngeal arch ISH
edn1tf216b/tf216b standard conditions Long-pec Not Detected hindbrain ISH
Long-pec pharyngeal arch ISH
nkx3-2 WT standard conditions Long-pec pharyngeal arch ISH
edn1tf216b/tf216b standard conditions Long-pec Not Detected pharyngeal arch ISH
wnt9a WT standard conditions Long-pec pharyngeal arch ISH
edn1tf216b/tf216b standard conditions Long-pec Not Detected pharyngeal arch ISH
Antibody Labeling Details No data available
Phenotype Details
Fish Conditions Stage Phenotype
edn1tf216b/tf216b standard conditions Long-pec hindbrain fzd7a expression absent, abnormal
Long-pec pharyngeal arch frzb expression absent, abnormal
Long-pec pharyngeal arch wnt9a expression absent, abnormal
Long-pec pharyngeal arch nkx3-2 expression absent, abnormal
Long-pec pharyngeal arch fzd7a expression decreased amount, abnormal
Acknowledgments:
ZFIN wishes to thank the journal Developmental Biology for permission to reproduce figures from this article. Please note that this material may be protected by copyright.

Reprinted from Developmental Biology, 381(2), Kamel, G., Hoyos, T., Rochard, L., Dougherty, M., Tse, W., Shubinets, V., Grimaldi, M., and Liao, E.C., Requirement for frzb and fzd7a in cranial neural crest convergence and extension mechanisms during zebrafish palate and jaw morphogenesis, 423-33, Copyright (2013) with permission from Elsevier. Full text @ Dev. Biol.