ZFIN Gene: fzd7a

ZFIN ID: ZDB-GENE-990415-223

ZFIN ID: ZDB-GENE-990415-223

Gene Name:

frizzled class receptor 7a

Gene Symbol:

fzd7a

Sequence Ontology ID :

SO:0001217

Previous Names:

fz7, zg07, id:ibd2735 (1), wu:fc17e10

Location:

Chr: 9 Mapping Details/Browsers

Nomenclature History

AUTOMATED DESCRIPTION

Predicted to have Wnt-activated receptor activity and Wnt-protein binding activity. Involved in chondrocyte proliferation; epiboly; and gastrulation. Localizes to the plasma membrane. Is expressed in ...

GENE EXPRESSION
All Expression Data:	32 figures from 11 publications
Directly Submitted Expression Data:	6 figures (20 images) from Thisse et al., 2004 [MGC:85603]
	3 figures (4 images) from Kudoh et al., 2001 [ibd2735]
	7 figures (17 images) from Thisse et al., 2005 [eu262]
Wild-type Stages, Structures:	Blastula:30%-epiboly (4.66h-5.25h) to Larval:Day 5 (120.0h-144.0h, 3.9mm, 6 teeth)
	basal plate midbrain region brain central nervous system diencephalon forebrain hindbrain hypothalamus inner ear hair cell margin mesenchyme midbrain neural plate neural rod neural tube optic tectum otic placode otic vesicle pectoral fin pectoral fin bud pharyngeal arch neural crest cell pharyngeal arch retina segmental plate somite spinal cord tegmentum unspecified ventral mandibular arch neural crest ventral mandibular arch ventral mesenchyme ventricular zone whole organism yolk syncytial layer
Curated Microarray Expression:	GEO (1)

MUTATIONS AND SEQUENCE TARGETING REAGENTS

Allele	Type	Localization	Consequence	Mutagen	Suppliers
e3	Point Mutation	Unknown	Premature Stop	ENU
sa10339	Point Mutation	Unknown	Premature Stop	ENU	European Zebrafish Resource Center (EZRC) (order this) Zebrafish International Resource Center (ZIRC) (order this)
sdu5	Indel	Exon 1	Unknown	TALEN

Targeting reagents:

PHENOTYPE

Data:

11 figures from 2 publications

Observed in:

DISEASE ASSOCIATED WITH fzd7a HUMAN ORTHOLOG No data available

DISEASE ASSOCIATED WITH fzd7a VIA EXPERIMENTAL MODELS No data available

GENE ONTOLOGY

Ontology	GO Term
Biological Process	convergent extension involved in gastrulation (more)
Cellular Component	plasma membrane (more)
Molecular Function	transmembrane signaling receptor activity (more)

GO Terms (all 15)

PROTEIN FAMILIES, DOMAINS AND SITES
InterPro:IPR000539 (1) InterPro:IPR015526 (1) InterPro:IPR017981 (1) InterPro:IPR020067 (1) InterPro:IPR026552 (1) InterPro:IPR036790 (1)	PROSITE:PS50038 (1) PROSITE:PS50261 (1)	Pfam:PF01392 (1) Pfam:PF01534 (1)

TRANSCRIPTS
Type	Name	Length (bp)	Analysis
mRNA	fzd7a-201 (1)	2764	Select Tool ZFIN BLAST NCBI BLAST Ensembl UCSC BLAT

GENE PRODUCT DESCRIPTION

INTERACTIONS AND PATHWAYS

ANTIBODIES No data available

PLASMIDS No data available

CONSTRUCTS WITH SEQUENCES FROM fzd7a No data available

MARKER RELATIONSHIPS

fzd7a Contained in:	[BAC] DKEY-62A12 (1) (order this)
fzd7a Encodes:	[EST] eu262 (1), fc17e10, ibd2735 (1) (order this) [cDNA] MGC:65759 (1) (order this), MGC:85603 (1) (order this)

SEQUENCE INFORMATION

Type	Accession #	Length (bp/aa)	Analysis
RNA	RefSeq:NM_131139 (1)	2768 bp	Select Tool ZFIN BLAST NCBI BLAST Ensembl UCSC BLAT
Genomic	GenBank:CR407547 (1)	204067 bp	Blast at MegaBLAST
Polypeptide	UniProtKB:Q6NV44 (1)	559 aa	Select Tool ZFIN BLAST SIB BLAST Ensembl Protein Blast
Sequence Clusters	UniGene:4823 (1)

Sequence Information (all 27)

OTHER fzd7a GENE PAGES

Alliance (1)

Gene:30369 (1)

VEGA:OTTDARG00000020395 (1)

Ensembl(GRCz11):ENSDARG00000060004 (1)

ORTHOLOGY for fzd7a ( Chr: 9 )

CITATIONS (59)

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